The nuclear receptor superfamily: A structural perspective
Sign Up to like & getrecommendations! Published in 2018 at "Protein Science"
DOI: 10.1002/pro.3496
Abstract: Nuclear receptors (NRs) are a family of transcription factors that regulate numerous physiological processes such as metabolism, reproduction, inflammation, as well as the circadian rhythm. NRs sense changes in lipid metabolite levels to drive differential… read more here.
Keywords: superfamily structural; receptor superfamily; physiology; nuclear receptor ... See more keywords
Structural Perspective of BMP ligands and Signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Bone"
DOI: 10.1016/j.bone.2020.115549
Abstract: The Bone Morphogenetic Proteins (BMPs) are the largest class signaling molecules within the greater Transforming Growth Factor Beta (TGFβ) family, and are responsible for a wide array of biological functions, including dorsal-ventral patterning, skeletal development… read more here.
Keywords: bmp; ligands signaling; perspective bmp; bmp ligands ... See more keywords
Mechanisms of ribosome recycling in bacteria and mitochondria: a structural perspective
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2067712
Abstract: ABSTRACT In all living cells, the ribosome translates the genetic information carried by messenger RNAs (mRNAs) into proteins. The process of ribosome recycling, a key step during protein synthesis that ensures ribosomal subunits remain available… read more here.
Keywords: mitochondria structural; bacteria mitochondria; mechanisms ribosome; ribosome recycling ... See more keywords
Immunomodulatory Proteins in Tick Saliva From a Structural Perspective
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.769574
Abstract: To feed successfully, ticks must bypass or suppress the host’s defense mechanisms, particularly the immune system. To accomplish this, ticks secrete specialized immunomodulatory proteins into their saliva, just like many other blood-sucking parasites. However, the… read more here.
Keywords: proteins tick; immunomodulatory proteins; saliva structural; immunomodulatory ... See more keywords
Proton-Translocating Nicotinamide Nucleotide Transhydrogenase: A Structural Perspective
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.01089
Abstract: Nicotinamide nucleotide transhydrogenase (TH) is an enzyme complex in animal mitochondria and bacteria that utilizes the electrochemical proton gradient across membranes to drive the production of NADPH. The enzyme plays an important role in maintaining… read more here.
Keywords: proton; nicotinamide nucleotide; proton translocating; structural perspective ... See more keywords
A Structural Perspective on Calprotectin as a Ligand of Receptors Mediating Inflammation and Potential Drug Target
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12040519
Abstract: Calprotectin, a heterodimer of S100A8 and S100A9 EF-hand calcium-binding proteins, is an integral part of the innate immune response. Calprotectin (CP) serves as a ligand for several pattern recognition cell surface receptors including the receptor… read more here.
Keywords: inflammation; perspective calprotectin; ligand; calprotectin ... See more keywords
A Structural Perspective on the RNA Editing of Plant Respiratory Complexes
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020684
Abstract: The last steps of respiration, a core energy-harvesting process, are carried out by a chain of multi-subunit complexes in the inner mitochondrial membrane. Several essential subunits of the respiratory complexes are RNA-edited in plants, frequently… read more here.
Keywords: rna editing; respiratory complexes; structural perspective; respiratory ... See more keywords
Interplay between Host tRNAs and HIV-1: A Structural Perspective
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13091819
Abstract: The cellular metabolism of host tRNAs and life cycle of HIV-1 cross paths at several key virus–host interfaces. Emerging data suggest a multi-faceted interplay between host tRNAs and HIV-1 that plays essential roles, both structural… read more here.
Keywords: interplay host; host trnas; host; hiv structural ... See more keywords