Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization
Sign Up to like & getrecommendations! Published in 2020 at "Protein Science"
DOI: 10.1002/pro.3941
Abstract: Bacterial microcompartments are protein‐based organelles that carry out specialized metabolic functions in diverse bacteria. Their outer shells are built from several thousand protein subunits. Some of the architectural principles of bacterial microcompartments have been articulated,… read more here.
Keywords: shell protein; structural polymorphism; symmetry breaking; breaking structural ... See more keywords
Cross-Seeded Fibrillation Induced by Pyroglutamate-3 and Truncated Aβ40 Variants Leads to Aβ40 Structural Polymorphism Modulation and Elevated Toxicity.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00341
Abstract: The pathological amyloid plaques in Alzheimer's disease (AD) patients contain not only the wild-type β-amyloid (wt-Aβ) peptide sequences but also a variety of post-translationally modified variants. The pyroglutamate-3 Aβ (pyroE3-Aβ), which is generated from its… read more here.
Keywords: fibrillation; structural polymorphism; cross seeded; seeded fibrillation ... See more keywords
Rapid evolution of a large structural polymorphism during a bacterial epidemic.
Sign Up to like & getrecommendations! Published in 2025 at "Heredity"
DOI: 10.1038/s41437-025-00812-7
Abstract: The field of population genetics is primarily focused on simple genetic variants such as single nucleotide polymorphisms (SNPs), small insertions or deletions (INDELs), and copy-number variants (CNVs). However, large-scale genomic variants are beginning to undergo… read more here.
Keywords: polymorphism; structural polymorphism; large structural; evolution large ... See more keywords
Structural polymorphism and diversity of human segmental duplications
Sign Up to like & getrecommendations! Published in 2025 at "Nature Genetics"
DOI: 10.1038/s41588-024-02051-8
Abstract: Segmental duplications (SDs) contribute significantly to human disease, evolution and diversity but have been difficult to resolve at the sequence level. We present a population genetics survey of SDs by analyzing 170 human genome assemblies… read more here.
Keywords: genetics; segmental duplications; structural polymorphism; polymorphism diversity ... See more keywords
Occurrence of structural polymorphism and supernumerary chromosomes in a population of Parodon nasus (Parodontidae)
Sign Up to like & getrecommendations! Published in 2017 at "Caryologia"
DOI: 10.1080/00087114.2017.1318503
Abstract: Abstract The family Parodontidae is a small group of fish that has distinct morphological differences. Despite its conserved diploid number, structural cytogenetic polymorphisms involving sex chromosomes are commonly described in this group. Conversely, reports on… read more here.
Keywords: parodon nasus; structural polymorphism; supernumerary chromosomes; group ... See more keywords
Salt-Induced Membrane-Bound Conformation of the NAC Domain of α-Synuclein Leads to Structural Polymorphism of Amyloid Fibrils
Sign Up to like & getrecommendations! Published in 2025 at "Biomolecules"
DOI: 10.3390/biom15040506
Abstract: α-Synuclein (αS) interacts with lipid membranes in neurons to form amyloid fibrils that contribute to Parkinson’s disease, and its non-amyloid-β component domain is critical in the fibrillation. In this study, the salt (NaCl) effect on… read more here.
Keywords: structural polymorphism; membrane bound; s57 102; membrane ... See more keywords
Influenza A Virus NS1 Protein Structural Flexibility Analysis According to Its Structural Polymorphism Using Computational Approaches
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031805
Abstract: Influenza A viruses are highly contagious RNA viruses that cause respiratory tract infections in humans and animals. Their non-structural protein NS1, a homodimer of two 230-residue chains, is the main viral factor in counteracting the… read more here.
Keywords: rna binding; three distinct; structural polymorphism; flexibility ... See more keywords
Structural Polymorphism of Single pDNA Condensates Elicited by Cationic Block Polyelectrolytes
Sign Up to like & getrecommendations! Published in 2020 at "Polymers"
DOI: 10.3390/polym12071603
Abstract: DNA folding is a core phenomenon in genome packaging within a nucleus. Such a phenomenon is induced by polyelectrolyte complexation between anionic DNA and cationic proteins of histones. In this regard, complexes formed between DNA… read more here.
Keywords: block; single pdna; dna; structural polymorphism ... See more keywords
Effects of a Low-Pass Filter on the Classification of Protein Electron-Density Maps in Terms of Structural Polymorphism using Manifold Learning: A Simulation Study for Cryo-Electron Microscopy Experiments
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Physical Society of Japan"
DOI: 10.7566/jpsj.88.094801
Abstract: Analyzing the structure of proteins in terms of their structural polymorphism has been recently performed using their two-dimensional electron-density maps obtained through cryo-electron microscopy... read more here.
Keywords: microscopy; density maps; electron; electron density ... See more keywords