Structural Refinement by Direct Mapping Reveals Assembly Inconsistencies near Hi-C Junctions
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DOI: 10.3390/plants12020320
Abstract: High-throughput chromosome conformation capture (Hi-C) is widely used for scaffolding in de novo assembly because it produces highly contiguous genomes, but its indirect statistical approach can introduce connection errors. We employed optical mapping (Bionano Genomics)… read more here.
Keywords: structural refinement; mapping reveals; optical mapping; refinement direct ... See more keywords