Articles with "structural variations" as a keyword



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Effects of Structural Variations on Antibacterial Properties for Conjugated Diynes Generated through Glaser Hay Couplings

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Published in 2022 at "Chemmedchem"

DOI: 10.1002/cmdc.202200455

Abstract: Antibiotic resistance is a growing problem facing global societies today. Many new antibiotics are derivatized versions of already existing antibiotics, which allows for antibiotic resistance to arise. To combat this issue, new antibiotics with different… read more here.

Keywords: effects structural; structural variations; properties conjugated; activity ... See more keywords
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Possible clinical implications of the structural variations between the tympanic membrane quadrants

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Published in 2022 at "Laryngoscope Investigative Otolaryngology"

DOI: 10.1002/lio2.861

Abstract: Retraction pockets and marginal perforations of the pars tensa of the tympanic membrane (TM) are most commonly found at superior posterior quadrant (SPQ). The patulous Eustachian tube tends to manifest in the same quadrant. Variation… read more here.

Keywords: membrane; implications structural; clinical implications; structural variations ... See more keywords
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Computational analysis of sequential and structural variations in stromelysins as an insight towards matrix metalloproteinase research

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Published in 2018 at "Informatics in Medicine Unlocked"

DOI: 10.1016/j.imu.2017.12.003

Abstract: Abstract Matrix metalloproteinases are zinc-dependent protein and peptide hydrolases. They are broadly involved in metabolic regulation through both extensive protein degradation and selective peptide-bond hydrolysis. Stromelysins belong to this group of proteinases and involved in… read more here.

Keywords: structural variations; sequential structural; analysis; predicted models ... See more keywords
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Analyzing structural variations along strike in a deep-water thrust belt

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Published in 2017 at "Journal of Structural Geology"

DOI: 10.1016/j.jsg.2017.06.007

Abstract: Abstract We characterize a deep-water fold-thrust arrays imaged by a high-resolution 3D seismic dataset in the offshore NW Borneo, Malaysia, to understand the kinematics behind spatial arrangement of structural variations throughout the fold-thrust system. The… read more here.

Keywords: along strike; structural variations; thrust; deep water ... See more keywords
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Structural variations, relationships and properties of M2B metal borides

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Published in 2019 at "Journal of Solid State Chemistry"

DOI: 10.1016/j.jssc.2018.12.014

Abstract: Abstract Metal borides represent a class of materials with a large variety of crystal structures, yet their physical and catalytic properties are overwhelmingly understudied. In this review, we present the structural variations, relationships and properties… read more here.

Keywords: metal borides; metal; relationships properties; properties m2b ... See more keywords
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Influence of Chromatin 3D Organization on Structural Variations of the Arabidopsis thaliana Genome.

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Published in 2017 at "Molecular plant"

DOI: 10.1016/j.molp.2016.09.015

Abstract: The spectrum of genetic variations ranges from single nucleotide polymorphisms (SNPs) to large-scale structural variants (SVs). Genome SVs involving kilobase- to megabase-sized insertions, deletions, duplications, and inversions, as well as complex combinations of rearrangements, are… read more here.

Keywords: structural variations; arabidopsis thaliana; organization structural; variations arabidopsis ... See more keywords
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Effect of Structural Variations on the Thermophysical Properties of Protic Ionic Liquids: Insights from Experimental and Computational Studies

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Published in 2017 at "Journal of Chemical & Engineering Data"

DOI: 10.1021/acs.jced.6b00450

Abstract: In this work, new protic ionic liquids (PILs) based on 1-methylimidazolium/1-propanenitrileimidazolium cations with hydrogen sulfate, methanesulfonate, trifluoromethanesulfonate, para-toluenesulfonate, trifluoroacetate, and acetate anions were synthesized. The structures and purity of the products were confirmed by using… read more here.

Keywords: structural variations; effect structural; protic ionic; variations thermophysical ... See more keywords
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Structural Variations of Lignin Macromolecules from Early Growth Stages of Poplar Cell Walls

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Published in 2019 at "ACS Sustainable Chemistry & Engineering"

DOI: 10.1021/acssuschemeng.9b05845

Abstract: The natural lignin macromolecule is structurally complex and heterogeneous polymers. Herein, to comprehend the dynamic structural characteristics of poplar (Populus tomentosa) lignin during the gro... read more here.

Keywords: structural variations; macromolecules early; early growth; lignin macromolecules ... See more keywords
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Accurate detection of complex structural variations using single molecule sequencing

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Published in 2018 at "Nature methods"

DOI: 10.1038/s41592-018-0001-7

Abstract: Structural variations are the greatest source of genetic variation, but they remain poorly understood because of technological limitations. Single-molecule long-read sequencing has the potential to dramatically advance the field, although high error rates are a… read more here.

Keywords: structural variations; detection; single molecule; long read ... See more keywords
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Single-cell structural variations

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Published in 2020 at "Nature Methods"

DOI: 10.1038/s41592-020-0787-y

Abstract: Somatic structural variations (SVs) underlie diseases such as cancer. While analysis of bulk DNA sequencing data allows SV detection, single-cell sequencing has the potential to characterize somatic SVs at higher resolution. Despite this conceptual appeal,… read more here.

Keywords: single cell; structural variations; cell structural; dna ... See more keywords
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Bleomycin-induced genome structural variations in normal, non-tumor cells

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-34580-8

Abstract: Many anticancer drugs are genotoxic agents inducing DNA breaks in actively proliferating cancer cells. However, these same drugs also induce mutations, mostly genome structural variations (GSVs). The detection of GSVs in normal cells and tissues… read more here.

Keywords: bleomycin induced; structural variations; normal cells; normal non ... See more keywords