Structurally diverse specialized metabolites of maize and their extensive biological functions.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.30955
Abstract: Maize originated in southern Mexico and various hybrid varieties have been bred during domestication. All maize tissues are rich in specialized plant metabolites (SPMs), which allow the plants to resist the stresses of herbivores and… read more here.
Keywords: specialized metabolites; metabolites maize; structurally diverse; diverse specialized ... See more keywords
Structurally diverse diterpenoids with eight carbon skeletons from Rhododendron micranthum and their antinociceptive effects.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104870
Abstract: Seventeen diterpenoids (1-17), classified into eight diverse carbon skeleton types, grayanane (1, 2, and 12), micranthane (3, 4, and 13), mollane (5-7 and 14), 1,5-seco-grayanane (8), kalmane (9-11), 1,5-seco-kalmane (15), A-homo-B-nor-ent-kaurane (16), and leucothane (17),… read more here.
Keywords: rhododendron micranthum; carbon; antinociceptive effects; seco kalmane ... See more keywords
Structurally diverse triterpenoids with cytotoxicity from Euphorbia hypericifolia.
Sign Up to like & getrecommendations! Published in 2021 at "Fitoterapia"
DOI: 10.1016/j.fitote.2021.104888
Abstract: Extensive phytochemical investigation on the whole herbs of Euphorbia hypericifolia led to the isolation of 18 structurally diverse tetracyclic and pentacyclic triterpenoids, including four 4α,14α-dimethyl-5α-ergostanes (1-4), two seco-adiananes (5 and 6), three dammaranes (7-9), four… read more here.
Keywords: cytotoxicity euphorbia; diverse triterpenoids; structurally diverse; triterpenoids cytotoxicity ... See more keywords
Structurally diverse limonoids and bio-active evaluation from Trichilia connaroides.
Sign Up to like & getrecommendations! Published in 2021 at "Fitoterapia"
DOI: 10.1016/j.fitote.2021.105001
Abstract: Four new limonoids, named as trichiconlide G (1), 2-hydroxyltrijugin F (2), 23-oxo-21-hydroxyltrijugin F (3), 21-oxo-23-hydroxyltrijugin F (4), along with sixteen known analogues (5-20) were isolated from the leaves and twigs of Trichilia connaroides. Their structures… read more here.
Keywords: trichilia connaroides; diverse limonoids; structurally diverse; oxo hydroxyltrijugin ... See more keywords
Combination of ozonation and electrolysis process to enhance elimination of thirty structurally diverse pharmaceuticals in aqueous solution.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2019.01.062
Abstract: The increasing amounts of pharmaceuticals in aqueous environment are found to be structurally diverse. O3 has been demonstrated as a high effective agent in removing pharmaceuticals, however, O3 is a very selective oxidant which is… read more here.
Keywords: ozonation; peroxone; process; structurally diverse ... See more keywords
Synthesis of new structurally diverse thiazolidinone-derived compounds based on reaction of isorhodanine with ortho-substituted aldehydes, α-keto- and β-aroylacrylic acids
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128448
Abstract: Abstract Various novel structurally diverse thiazolidinone-derived compounds were synthesized from isorhodanine (4-thioxo-2-thiazolidinone) with ortho-substituted aldehydes, arylidene pyruvic and β-aroylacrylic acids. Michael reaction of isorhodanine with arylidene pyruvic and β-aroylacrylic acids providing 2-oxo-4-(2-oxo-4-thioxothiazolidin-5-yl)-4-phenylbutyric and 4-oxo-2-(2-oxo-2,3-dihydrothiazol-4-ylsulfanyl)-4-phenylbutyric acid… read more here.
Keywords: aroylacrylic acids; thiazolidinone derived; thiazolidinone; structurally diverse ... See more keywords
Biodegradation of Structurally Diverse Phthalate Esters by a Newly Identified Esterase with Catalytic Activity toward Di(2-ethylhexyl) Phthalate.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b02655
Abstract: Herein, we report a double enzyme system to degrade 12 phthalate esters (PAEs), particularly bulky PAEs, such as the widely-used di(2-ethylhexyl) phthalate (DEHP), in a one-pot cascade process. A PAE-degrading bacterium, Gordonia sp. strain 5F,… read more here.
Keywords: phthalate; diverse phthalate; phthalate esters; structurally diverse ... See more keywords
Interaction of structurally diverse phenolic compounds with porcine pancreatic α-amylase.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b04798
Abstract: A blood glucose level lowering effect is postulated for polyphenols (PPs), which is in part attributed to the inhibition of α-amylase. To estimate structure-effect relationships chlorogenic acid (CA), phlorizin (PHL), epigallocatechin gallate (EGCG), epicatechin (EC)… read more here.
Keywords: diverse phenolic; amylase; structurally diverse; interaction ... See more keywords
Comprehensive 3D-QSAR Model Predicts Binding Affinity of Structurally Diverse Sigma 1 Receptor Ligands
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00521
Abstract: The Sigma 1 Receptor (S1R) has attracted intense interest as a pharmaceutical target for various therapeutic indications, including the treatment of neuropathic pain and the potentiation of opioid analgesia. Efforts by drug developers to rationally… read more here.
Keywords: s1r antagonists; qsar model; structurally diverse; model ... See more keywords
Fragment Libraries Designed to Be Functionally Diverse Recover Protein Binding Information More Efficiently Than Standard Structurally Diverse Libraries
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c01004
Abstract: Current fragment-based drug design relies on the efficient exploration of chemical space though the use of structurally diverse libraries of small fragments. However, structurally dissimilar compounds can exploit the same interactions on a target, and… read more here.
Keywords: information; diverse libraries; structurally diverse; functionally diverse ... See more keywords
Structurally Diverse Sesquiterpenoid Glycoside Esters from Pittosporum qinlingense with Anti-neuroinflammatory Activity.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00544
Abstract: Thirteen new sesquiterpenoid glycoside esters, including 11 aromadendrane-type compounds, pitqinlingosides A-K (1-11), one cadinane-type compound, pitqinlingoside L (12), and one eudesmane-type compound, pitqinlingoside M (13), together with seven known analogues (14-20) were isolated from the… read more here.
Keywords: glycoside esters; pittosporum qinlingense; glycoside; sesquiterpenoid glycoside ... See more keywords