LAUSR

Association Between Brain Structure and Alcohol Use Behaviors in Adults

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2 Published in 2022 at "JAMA Psychiatry"

DOI: 10.1001/jamapsychiatry.2022.2196

Abstract: Key Points Question Are there directional associations between cortical or subcortical macrostructure and alcohol use? Findings This mendelian randomization study including 763 874 participants in UK Biobank, Enhancing NeuroImaging Genetics through Meta Analysis (ENIGMA), Psychiatric Genomics… read more here.

Keywords: structure; association brain; alcohol use; alcohol ... See more keywords

Crystal structure and functional characterization of SF216 from Shigella flexneri

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0 Published in 2017 at "FEBS Letters"

DOI: 10.1002/1873-3468.12873

Abstract: Shigella flexneri is a Gram‐negative anaerobic bacterium that causes highly infectious bacterial dysentery in humans. Here, we solved the crystal structure of SF216, a hypothetical protein from the S. flexneri 5a strain M90T, at 1.7… read more here.

Keywords: crystal structure; structure functional; structure; shigella flexneri ... See more keywords

Function and structure relationships of a β‐1,2‐glucooligosaccharide‐degrading β‐glucosidase

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1 Published in 2017 at "FEBS Letters"

DOI: 10.1002/1873-3468.12911

Abstract: BT_3567 protein, a putative β‐glucosidase from Bacteroides thetaiotaomicron, exhibits higher activity toward Sop3–5 (Sopn, n: degree of polymerization of β‐1,2‐glucooligosaccharides) than toward Sop2, unlike a known β‐glucosidase from Listeria innocua which predominantly prefers Sop2. In… read more here.

Keywords: relationships glucooligosaccharide; glucooligosaccharide degrading; structure relationships; function structure ... See more keywords

Linker histone H1FOO regulates the chromatin structure in mouse zygotes

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1 Published in 2018 at "FEBS Letters"

DOI: 10.1002/1873-3468.13175

Abstract: The chromatin structure in one‐cell‐stage mouse embryos is extremely loose and becomes tighter at the two‐cell stage. As linker histones are involved in higher‐order chromatin structure, we examined the involvement of the linker histone variant… read more here.

Keywords: chromatin structure; h1foo; structure; cell ... See more keywords

Domain structure of HelD, an interaction partner of Bacillus subtilis RNA polymerase

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1 Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13385

Abstract: The HelD is a helicase‐like protein binding to Bacillus subtilis RNA polymerase (RNAP), stimulating transcription in an ATP‐dependent manner. Here, our small angle X‐ray scattering data bring the first insights into the HelD structure: HelD… read more here.

Keywords: domain structure; rna polymerase; structure held; structure ... See more keywords

Structure and steroid isomerase activity of Drosophila glutathione transferase E14 essential for ecdysteroid biosynthesis

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0 Published in 2019 at "FEBS Letters"

DOI: 10.1002/1873-3468.13718

Abstract: Ecdysteroids are critically important for the formation of the insect exoskeleton. Cholesterol is a precursor of ecdysone and its active form 20‐hydroxyecdysone, but some steps in the ecdysteroid biosynthesis pathway remain unknown. An essential requirement… read more here.

Keywords: isomerase activity; biosynthesis; transferase; ecdysteroid biosynthesis ... See more keywords

The structure of myeloid cell‐specific TNF inhibitors affects their biological properties

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1 Published in 2020 at "FEBS Letters"

DOI: 10.1002/1873-3468.13913

Abstract: Spatial organization and conformational changes of antibodies may significantly affect their biological functions. We assessed the effect of mutual organization of the two VHH domains within bispecific antibodies recognizing human TNF and the surface molecules… read more here.

Keywords: tnf; specific tnf; structure myeloid; myeloid cell ... See more keywords

The first crystal structure of a xylobiose‐bound xylobiohydrolase with high functional specificity from the bacterial glycoside hydrolase family 30, subfamily 10

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1 Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14454

Abstract: Xylobiose is a prebiotic sugar that has applications in functional foods. This report describes the first X‐ray crystallographic structure models of apo and xylobiose‐bound forms of a xylobiohydrolase (XBH) from Acetivibrio clariflavus. This xylan‐active enzyme,… read more here.

Keywords: structure; glycoside hydrolase; xylobiose bound; high functional ... See more keywords

Crystal structure of the Fusarium oxysporum tannase‐like feruloyl esterase FaeC in complex with p‐coumaric acid provides insight into ligand binding

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2 Published in 2023 at "FEBS Letters"

DOI: 10.1002/1873-3468.14615

Abstract: Feruloyl esterases (FAEs) hydrolyze the ester bonds between hydroxycinnamic acids and arabinose residues of plant cell walls and exhibit considerable diversity in terms of substrate specificity. Here, we report the crystal structure of an FAE… read more here.

Keywords: coumaric acid; structure; fusarium oxysporum; tannase like ... See more keywords

Constraining Sedimentary Structure Using Frequency‐Dependent P Wave Particle Motion: A Case Study of the Songliao Basin in NE China

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1 Published in 2017 at "Journal of Geophysical Research"

DOI: 10.1002/2017jb014721

Abstract: Knowledge on sedimentary structure within a basin is of great importance for exploring petroleum resources and predicting strong ground motions caused by earthquakes. Although 3-D seismic data acquisition is common nowadays in petroleum industry, it… read more here.

Keywords: wave; structure; frequency dependent; using frequency ... See more keywords

Characterization of the structure and cross‐shore transport properties of a coastal upwelling filament using three‐dimensional finite‐size Lyapunov exponents

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0 Published in 2017 at "Journal of Geophysical Research"

DOI: 10.1002/2017jc012700

Abstract: The three dimensional structure, dynamics and dispersion characteristics of a simulated upwelling filament in the Iberian upwelling system are analyzed using Lagrangian tools. We used a realistic regional simulation of the western Iberian shelf which… read more here.

Keywords: three dimensional; finite size; size lyapunov; upwelling filament ... See more keywords