Articles with "structure atropisomer" as a keyword



Structure‐Atropisomer Stability Relationship in Selective MCL‐1 Inhibitors

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Published in 2025 at "ChemMedChem"

DOI: 10.1002/cmdc.202400970

Abstract: Atropisomersm is an emerging feature in recent drug candidates due to the increasing complexity of the targeted protein surfaces. The developability of the drug candidates requires that their atropisomer interconversion is either fast or very… read more here.

Keywords: selective mcl; stability; mcl inhibitors; structure atropisomer ... See more keywords