Biophysical study of bevacizumab structure and bioactivity under thermal and pH‐stresses
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2017.05.019
Abstract: ABSTRACT The evaluation of the structural stability and bioactivity of monoclonal antibodies (mAb) is a crucial step in the development of mAb therapeutic based products, since immunogenicity needs to be avoided. In the present work,… read more here.
Keywords: bioactivity; bevacizumab; temperature; structure bioactivity ... See more keywords
Triphenyltin(IV) acylhydrazone compounds: Synthesis, structure and bioactivity.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2018.11.011
Abstract: Four new triphenyltin(IV) acylhydrazone compounds of the type Ph3SnCH2CH2CONHN=R (where Ph = phenyl; R = isopropyl, isobutyl, cyclopentyl and cyclooctyl) were synthesized and characterized by elemental analysis, infrared spectrum (IR), nuclear magnetic resonance spectrum (NMR) and mass spectrum (MS).… read more here.
Keywords: triphenyltin acylhydrazone; compounds synthesis; structure bioactivity; acylhydrazone compounds ... See more keywords
Influence of strontium on structure, bioactivity and corrosion behaviour of B2O3–SiO2–Na2O–CaO glasses-investigation by spectroscopic methods
Sign Up to like & getrecommendations! Published in 2018 at "Optical Materials"
DOI: 10.1016/j.optmat.2018.07.024
Abstract: Abstract Strontium mixed borate based bioactive glasses of the composition (55–x)B2O3–5SiO2–20CaO–20Na2O: xSrO (with x = 2,4,6,8 and 10 mol%) were synthesized using conventional melt quenching technique. Structural variations in the glasses due to addition of SrO were assessed… read more here.
Keywords: bioactivity; structure bioactivity; influence strontium; strontium ... See more keywords
Structure-Bioactivity Relationship Study of Xanthene Derivatives: A Brief Review.
Sign Up to like & getrecommendations! Published in 2019 at "Current organic synthesis"
DOI: 10.2174/1570179416666191017094908
Abstract: Over the last decades, several heterocyclic derivatives compounds have been synthesized or extracted from natural resources and have been tested for their pharmaceutical activities. Xanthene is one of these heterocyclic derivatives. These compounds consist of… read more here.
Keywords: structure bioactivity; bioactivity relationship; xanthene derivatives; structure ... See more keywords
Synthesis, Crystal Structure and Bioactivity of Phenazine-1-carboxylic Acylhydrazone Derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26175320
Abstract: A phenazine-1-carboxylic acid intermediate was synthesized from the reaction of aniline and 2-bromo-3-nitro-benzoic acid. It was then esterified and reacted with hydrazine hydrate to afford phenazine-1-carboxylic hydrazine. Finally, 10 new hydrazone compounds 3a–3j were obtained… read more here.
Keywords: crystal structure; structure bioactivity; phenazine; phenazine carboxylic ... See more keywords