Crystal structure of PD-1 in complex with an antibody-drug tislelizumab used in tumor immune checkpoint therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.04.121
Abstract: Blocking of the interaction between Programmed cell death 1 (PD-1) and its ligand PD-L1 by monoclonal antibodies has elicited unprecedented therapeutic benefits and achieved a major breakthrough in immunotherapy of multiple types of tumors. Here,… read more here.
Keywords: crystal structure; interaction; antibody; structure complex ... See more keywords
Structure of the complex of cytochrome c with cardiolipin in non-polar environment.
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2018.05.007
Abstract: The complex of mitochondrial protein cytochrome c (CytC) with anionic phospholipid cardiolipin (CL) plays a crucial role in the initiation of apoptosis by catalyzing lipid peroxidation in mitochondrial membranes. In our previous papers, we found… read more here.
Keywords: cyt; cardiolipin; cytochrome; structure complex ... See more keywords