Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inflammatory Diseases.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c01996
Abstract: Soluble epoxide hydrolase (sEH) has been identified as an attractive target for anti-inflammatory drug design in recent years. Picomolar level compound G1 against sEH was obtained by introducing the hydrophilic group homopiperazine and hydrophobic fragment… read more here.
Keywords: treatment; structure directed; soluble epoxide; epoxide hydrolase ... See more keywords
Pore-structure-directed CO2 electroreduction to formate on SnO2/C catalysts
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry A"
DOI: 10.1039/c9ta05937g
Abstract: Three-dimensional porous carbon sheets with abundant micropores and macropores are used to uniformly disperse SnO2 nanoparticles with high loading, and the obtained SnO2/PC exhibits efficient formate production from electrochemical CO2 reduction. read more here.
Keywords: directed co2; co2 electroreduction; pore structure; sno2 ... See more keywords
Studying Asymmetric Structure in Directed Networks by Overlapping and Non-Overlapping Models
Sign Up to like & getrecommendations! Published in 2022 at "Entropy"
DOI: 10.3390/e24091216
Abstract: We consider the problem of modeling and estimating communities in directed networks. Models to this problem in the previous literature always assume that the sending clusters and the receiving clusters have non-overlapping property or overlapping… read more here.
Keywords: asymmetric structure; overlapping property; directed networks; structure directed ... See more keywords