Structure and Gating Dynamics of Na+/Cl– Coupled Neurotransmitter Transporters
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2019.00080
Abstract: Neurotransmitters released at the neural synapse through vesicle exocytosis are spatiotemporally controlled by the action of neurotransmitter transporters. Integral membrane proteins of the solute carrier 6 (SLC6) family are involved in the sodium and chloride… read more here.
Keywords: neurotransmitter transporters; structure gating; gating dynamics; dynamics coupled ... See more keywords
Structure and gating of kainate receptors
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2025.1662316
Abstract: Ionotropic glutamate receptors (iGluRs) are crucial for fast excitatory neurotransmission in the mammalian central nervous system (CNS). Kainate receptors (KARs), a subclass of iGluRs, are tetrameric, ligand-gated ion channels that play key modulatory roles at… read more here.
Keywords: pharmacology; gating kainate; biology; structure gating ... See more keywords