Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery
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DOI: 10.7554/elife.80901
Abstract: Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and pathogenic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requires HOPS, a conserved heterohexameric tethering complex. On the membranes to be… read more here.
Keywords: fusion; membrane fusion; tethering complex; structure hops ... See more keywords