Experimental Band Structure of Pb(Zr,Ti)O3: Mechanism of Ferroelectric Stabilization
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202205476
Abstract: Pb(Zr,Ti)O3 (PZT) is the most common ferroelectric (FE) material widely used in solid‐state technology. Despite intense studies of PZT over decades, its intrinsic band structure, electron energy depending on 3D momentum k, is still unknown.… read more here.
Keywords: pzt; band structure; structure mechanism; experimental band ... See more keywords
RNases H: Structure and mechanism.
Sign Up to like & getrecommendations! Published in 2019 at "DNA repair"
DOI: 10.1016/j.dnarep.2019.102672
Abstract: RNases H are a family of endonucleases that hydrolyze RNA residues in various nucleic acids. These enzymes are present in all branches of life, and their counterpart domains are also found in reverse transcriptases (RTs)… read more here.
Keywords: structure mechanism; mechanism; cleavage; rnase ... See more keywords
Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.12.010
Abstract: Bacteria possess an array of defenses against foreign invaders, including a broadly distributed bacteriophage defense system termed CBASS (cyclic oligonucleotide-based anti-phage signaling system). In CBASS systems, a cGAS/DncV-like nucleotidyltransferase synthesizes cyclic di- or tri-nucleotide second… read more here.
Keywords: structure mechanism; mechanism cyclic; bacteriophage immunity; bacteriophage ... See more keywords
Structure, mechanism, and inhibition of Hedgehog acyltransferase
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cell"
DOI: 10.1016/j.molcel.2021.11.018
Abstract: Summary The Sonic Hedgehog (SHH) morphogen pathway is fundamental for embryonic development and stem cell maintenance and is implicated in various cancers. A key step in signaling is transfer of a palmitate group to the… read more here.
Keywords: structure mechanism; hedgehog acyltransferase; structure; mechanism inhibition ... See more keywords
Structure, mechanism, and inhibition of the zinc-dependent histone deacetylases.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2019.01.004
Abstract: Zinc-dependent histone deacetylases (HDACs) regulate the biological function of histone and non-histone proteins through the hydrolysis of acetyllysine side chains to yield free lysine and acetate. Certain HDAC isozymes exhibit alternative catalytic activities, such as… read more here.
Keywords: zinc dependent; structure mechanism; dependent histone; histone deacetylases ... See more keywords
cGAS and CD-NTase enzymes: structure, mechanism, and evolution
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Structural Biology"
DOI: 10.1016/j.sbi.2019.08.003
Abstract: Cyclic GMP–AMP synthase (cGAS) is a signaling enzyme in human cells that controls immune-sensing of cytosolic DNA. The recent discoveries of diverse structural homologs of cGAS in animals and bacteria reveal that cGAS-like signaling is… read more here.
Keywords: cgas; structure mechanism; enzymes structure; biology ... See more keywords
Structure and mechanism of the γ-secretase intramembrane protease complex.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2022.102373
Abstract: γ-Secretase is a membrane protein complex that proteolyzes within the transmembrane domain of >100 substrates, including those derived from the amyloid precursor protein and the Notch family of cell surface receptors. The nine-transmembrane presenilin is… read more here.
Keywords: structure mechanism; protease complex; structure; secretase ... See more keywords
Structure and Mechanism of a Cold-Adapted Bacterial Lipase
Sign Up to like & getrecommendations! Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00087
Abstract: The structural origin of enzyme cold-adaptation has been the subject of considerable research efforts in recent years. Comparative studies of orthologous mesophilic–psychrophilic enzyme pairs found in nature are an obvious strategy for solving this problem,… read more here.
Keywords: mechanism cold; structure mechanism; sequence; cold adapted ... See more keywords
Structure and Mechanism Revision of a Catalyzed Cyclization of Benzaldehyde Bearing Alkyne-Nitrile.
Sign Up to like & getrecommendations! Published in 2017 at "Organic letters"
DOI: 10.1021/acs.orglett.7b01881
Abstract: Pt(II)-catalyzed carbocyclization of benzaldehyde containing a keto-nitrile functionality resulted in the formation, respectively, of isochromenes and spiro-lactones instead of fused lactams and spiro-lactams as was previously reported. The reaction mechanism was proposed, and the products… read more here.
Keywords: structure mechanism; benzaldehyde; revision catalyzed; mechanism ... See more keywords
Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c09412
Abstract: Terpene cyclases (TCs), extraordinary enzymes that create the structural diversity seen in terpene natural products, are traditionally divided into two classes, class I and class II. Although the structural and mechanistic features of class I… read more here.
Keywords: class sesquiterpene; class; structure mechanism; discovery structure ... See more keywords
Structure and mechanism for iterative amide N-methylation in the biosynthesis of channel-forming peptide cytotoxins
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2116578119
Abstract: Significance The channel-forming proteusins are bacterial helical peptides that allow permeation of positively charged ions to influence membrane potential and cellular physiology. We biochemically characterize the effect of two critical posttranslational modifications on the secondary… read more here.
Keywords: structure mechanism; iterative amide; mechanism iterative; channel forming ... See more keywords