Structure Modification of FXR Antagonistic Chalcones and Their Inhibitory Effects on NSCLC Cell Proliferation and Metastasis
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202100778
Abstract: Although the farnesoid X receptor (FXR) has been regarded as a promising drug target for metabolic diseases as well as anti‐inflammatory, antitumor and antiviral actions, the antagonism by FXR ligands are still underrepresented in current… read more here.
Keywords: metastasis; cell proliferation; nsclc cell; modification fxr ... See more keywords
Influence of Structure Modification of Silicon Carbide Materials on Their Dynamic Properties
Sign Up to like & getrecommendations! Published in 2018 at "Refractories and Industrial Ceramics"
DOI: 10.1007/s11148-018-0236-y
Abstract: SiC ceramic materials were prepared both by reactive and liquid-phase sintering. Structure was modified during preparation by introducing reinforcing SiC-filaments and by synthesizing grains self-reinforcing the structure. The armor-protection capacity was determined by estimating the… read more here.
Keywords: silicon carbide; carbide materials; influence structure; modification silicon ... See more keywords
Band structure modification of g-C3N4 for efficient heterojunction construction and enhanced photocatalytic capability under visible light irradiation
Sign Up to like & getrecommendations! Published in 2019 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2019.01.003
Abstract: Abstract The graphene (Gr)/PI (pyromellitic dianhydride (PMDA) modified g-C3N4) heterojunction was fabricated by a handy sonochemical method. After adding PMDA in the forming process of g-C3N4, the conduction position of obtained catalyst was lowered to… read more here.
Keywords: c3n4; structure modification; modification c3n4; heterojunction ... See more keywords
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds
Sign Up to like & getrecommendations! Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-018-0087-6
Abstract: The serum and glucocorticoid-regulated kinase (SGK) family has been implicated in the regulation of many cellular processes downstream of the PI3K pathway. It plays a crucial role in PI3K-mediated tumorigenesis, making it a potential therapeutic… read more here.
Keywords: modification characterization; sgk3; identification structure; structure modification ... See more keywords
Crystal structure modification enhances air stability and suppresses O2 evolution in Li5FeO4: insights from experiments and DFT calculations
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Materials Chemistry A"
DOI: 10.1039/d5ta01549a
Abstract: The usage of Li5FeO4 (LFO) as a prelithiation additive in cathodes to improve battery energy density stands out as an excellent option, boasting a remarkable theoretical specific capacity and the... read more here.
Keywords: structure modification; li5feo4; crystal structure; air stability ... See more keywords
Novel AIEEgens: Small Structure Modification with Significant Property Change
Sign Up to like & getrecommendations! Published in 2024 at "Synthesis"
DOI: 10.1055/a-2518-0946
Abstract: In this study, a series of small molecules based on 3-(dimethylamino)-1-(2-hydroxyphenyl)-2-propen-1-one have been prepared under mild reaction conditions. Most of the compounds showed high fluorescence quantum yield in the solid-state (Φ Fmax = 0.75). In… read more here.
Keywords: small structure; structure modification; significant property; novel aieegens ... See more keywords
Recent advances in the improvement of enzyme thermostability by structure modification
Sign Up to like & getrecommendations! Published in 2019 at "Critical Reviews in Biotechnology"
DOI: 10.1080/07388551.2019.1682963
Abstract: Abstract Thermostability is considered to be an important parameter to measure the feasibility of enzymes for industrial applications. Generally, higher thermostability makes an enzyme more competitive and desirable in industry. However, most natural enzymes show… read more here.
Keywords: enzyme thermostability; thermostability; improvement enzyme; structure modification ... See more keywords
Structure modification and anti-tumor activity evaluation on sesquiterpene lactones TBA and TBB from Sphagneticola trilobata.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2151009
Abstract: Thirteen sesquiterpene lactone derivatives were designed and synthesised using the sesquiterpene lactone epimers TBA and TBB as the parent molecules, isolated from Sphagneticola trilobata. Their structures were elucidated by extensive spectroscopic studies and chemical evidence.… read more here.
Keywords: tba tbb; sesquiterpene; activity; sphagneticola trilobata ... See more keywords
Electronic structure modification in Fe-substituted β-Ga2O3 from resonant photoemission and soft x-ray absorption spectroscopies
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Physics D: Applied Physics"
DOI: 10.1088/1361-6463/ac43dc
Abstract: Oriented thin films of β-(Ga1−x Fe x )2O3 were deposited by radio frequency magnetron sputtering on c-Al2O3 and GaN substrates. The itinerant character of the Fe 3d states forming the top of the valence band… read more here.
Keywords: ga2o3 resonant; electronic structure; physics; modification substituted ... See more keywords
Structure Modification of High-Nitrogen and High-Carbon Austenitic Steels by Megadeformation
Sign Up to like & getrecommendations! Published in 2018 at "Physics of Metals and Metallography"
DOI: 10.1134/s0031918x18110182
Abstract: This study has established the change in the kinetics of the deformation-induced dissolution and precipitation of carbides and nitrides in austenitic steels supersaturated with nitrogen and carbon due to the continuous generation of point defects… read more here.
Keywords: carbon; austenitic steels; high nitrogen; nitrogen high ... See more keywords
The Synthesis, Crystal Structure, Modification, and Cytotoxic Activity of α-Hydroxy-Alkylphosphonates
Sign Up to like & getrecommendations! Published in 2025 at "Molecules"
DOI: 10.3390/molecules30020428
Abstract: A series of α-hydroxy-alkylphosphonates and α-hydroxy-alkylphosphine oxides were synthesized by the Pudovik reaction of acetaldehyde and acetone with dialkyl phosphites or diarylphosphine oxides. The additions were performed in three different ways: in liquid phase using… read more here.
Keywords: structure modification; crystal structure; hydroxy; hydroxy alkylphosphonates ... See more keywords