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Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202100778
Abstract: Although the farnesoid X receptor (FXR) has been regarded as a promising drug target for metabolic diseases as well as anti‐inflammatory, antitumor and antiviral actions, the antagonism by FXR ligands are still underrepresented in current… read more here.
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Published in 2018 at "Refractories and Industrial Ceramics"
DOI: 10.1007/s11148-018-0236-y
Abstract: SiC ceramic materials were prepared both by reactive and liquid-phase sintering. Structure was modified during preparation by introducing reinforcing SiC-filaments and by synthesizing grains self-reinforcing the structure. The armor-protection capacity was determined by estimating the… read more here.
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Published in 2019 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2019.01.003
Abstract: Abstract The graphene (Gr)/PI (pyromellitic dianhydride (PMDA) modified g-C3N4) heterojunction was fabricated by a handy sonochemical method. After adding PMDA in the forming process of g-C3N4, the conduction position of obtained catalyst was lowered to… read more here.
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Published in 2018 at "Acta Pharmacologica Sinica"
DOI: 10.1038/s41401-018-0087-6
Abstract: The serum and glucocorticoid-regulated kinase (SGK) family has been implicated in the regulation of many cellular processes downstream of the PI3K pathway. It plays a crucial role in PI3K-mediated tumorigenesis, making it a potential therapeutic… read more here.
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Published in 2019 at "Critical Reviews in Biotechnology"
DOI: 10.1080/07388551.2019.1682963
Abstract: Abstract Thermostability is considered to be an important parameter to measure the feasibility of enzymes for industrial applications. Generally, higher thermostability makes an enzyme more competitive and desirable in industry. However, most natural enzymes show… read more here.
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Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2151009
Abstract: Thirteen sesquiterpene lactone derivatives were designed and synthesised using the sesquiterpene lactone epimers TBA and TBB as the parent molecules, isolated from Sphagneticola trilobata. Their structures were elucidated by extensive spectroscopic studies and chemical evidence.… read more here.
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Published in 2021 at "Journal of Physics D: Applied Physics"
DOI: 10.1088/1361-6463/ac43dc
Abstract: Oriented thin films of β-(Ga1−x Fe x )2O3 were deposited by radio frequency magnetron sputtering on c-Al2O3 and GaN substrates. The itinerant character of the Fe 3d states forming the top of the valence band… read more here.
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Published in 2018 at "Physics of Metals and Metallography"
DOI: 10.1134/s0031918x18110182
Abstract: This study has established the change in the kinetics of the deformation-induced dissolution and precipitation of carbides and nitrides in austenitic steels supersaturated with nitrogen and carbon due to the continuous generation of point defects… read more here.
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Published in 2023 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2022-0309
Abstract: Prodrug strategy is critical for innovative drug development. Structural modification is the most straightforward and effective method to develop prodrugs. Improving drug defects and optimizing the physical and chemical properties of a drug, such as… read more here.