CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction
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DOI: 10.1126/sciadv.1701264
Abstract: CryoEM structure of MxB tubes at 4.6 Å resolution reveals novel interfaces responsible for assembly and anti–HIV-1 activity. Human dynamin–like, interferon-induced myxovirus resistance 2 (Mx2 or MxB) is a potent HIV-1 inhibitor. Antiviral activity requires… read more here.
Keywords: cryoem structure; mxb; reveals novel; hiv ... See more keywords