Crystal structure of parallel G-quadruplex formed by the two-repeat ALS- and FTD-related GGGGCC sequence
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DOI: 10.1093/nar/gkab302
Abstract: Abstract The hexanucleotide repeat expansion, GGGGCC (G4C2), within the first intron of the C9orf72 gene is known to be the most common genetic cause of both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The… read more here.
Keywords: crystal structure; g4c2; repeat; als ftd ... See more keywords