Substitution of iron with cobalt in the prosthetic group of bacterial cytochrome P450: Effects on the stability and structure of the protein
Sign Up to like & getrecommendations! Published in 2019 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2018.12.043
Abstract: Abstract The origin of thermostability of the heme monooxygenase from Thermus thermophilus, CYP175A1 has been investigated using multi-wavelength circular dichroism (CD) spectroscopy at different temperatures. The far-UV and visible CD studies were carried out on… read more here.
Keywords: prosthetic group; wtcyp175a1; stability; structure protein ... See more keywords
Crystal structure of a protein-aromatic foldamer composite: macromolecular chiral resolution.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc05330a
Abstract: Co-crystallization of a 2 kDa tether-free sulfonated foldamer and the 13 kDa lysine-rich cytochrome c yielded a remarkable biohybrid assembly with chiral resolution of the foldamer helix handedness. In the crystal a ∼5 nm foldamer… read more here.
Keywords: crystal structure; foldamer; structure protein; chiral resolution ... See more keywords
Hierarchical Structure of Protein Sequence
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22158339
Abstract: Most non-communicable diseases are associated with dysfunction of proteins or protein complexes. The relationship between sequence and structure has been analyzed for a long time, and the analysis of the sequences organization in domains and… read more here.
Keywords: protein; hierarchical structure; protein sequence; structure protein ... See more keywords
Hydrophobic Interactions Drive Binding between Vascular Endothelial Growth Factor-A (VEGFA) and Polyphenolic Inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24152785
Abstract: Some polyphenols have been shown to inhibit, at physiological levels, the VEGF-induced VEGF receptor-2 signaling that causes angiogenesis, allegedly by direct interaction with VEGF and reducing the binding to its receptor VEGFR2. Surface plasmon resonance… read more here.
Keywords: hydrophobic interactions; interactions drive; secondary structure; structure protein ... See more keywords
Using Neural Networks to Predict Secondary Structure for Protein Folding
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Computational Chemistry"
DOI: 10.4236/jcc.2017.51001
Abstract: Protein Secondary Structure Prediction (PSSP) is considered as one of the major challenging tasks in bioinformatics, so many solutions have been proposed to solve that problem via trying to achieve more accurate prediction results. The… read more here.
Keywords: protein; predict secondary; secondary structure; structure protein ... See more keywords