FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation.
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DOI: 10.1158/0008-5472.can-18-0631
Abstract: Cooperativity between WNT and FGF signaling is well documented in embryonic development and cancer progression, but the molecular mechanisms underlying this cross-talk remain elusive. In this study, we interrogated the dynamics of RNA levels, ribosome… read more here.
Keywords: wnt; fgf signaling; translation; pathway components ... See more keywords