Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding
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DOI: 10.1093/nar/gkac774
Abstract: Abstract The introduction of phosphorothioate (PS) linkages to the backbone of therapeutic nucleic acids substantially increases their stability and potency. It also affects their interactions with cellular proteins, but the molecular mechanisms that underlie this… read more here.
Keywords: annexin dna; dna; complexes show; dna complexes ... See more keywords