Triarylamine-Based Supramolecular Polymers: Structures, Dynamics, and Functions.
Sign Up to like & getrecommendations! Published in 2019 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.8b00536
Abstract: Triarylamine molecules and triarylamine-based covalent polymers have been extensively investigated for more than 60 years in academics and industry because of their intriguing electronic and optical characteristics. However, despite the profusion of studies made on… read more here.
Keywords: triarylamine based; functions triarylamine; structures dynamics; supramolecular polymers ... See more keywords
Structures and Dynamics of β-Rich Oligomers of ATTR (105-115) Assembly.
Sign Up to like & getrecommendations! Published in 2024 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00574
Abstract: Transthyretin (TTR) is a tetrameric homologous protein that can dissociate into monomers. Misfolding and aggregation of TTR can lead to amyloid transthyretin amyloidosis (ATTR), which can cause many diseases (e.g., senile systemic amyloidosis, familial amyloid… read more here.
Keywords: attr 105; rich oligomers; 105 115; dynamics rich ... See more keywords
Exploring Structures and Dynamics of Protamine Molecules through Molecular Dynamics Simulations
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04227
Abstract: Protamines are arginine-rich proteins that condense DNA in sperm. Despite their importance in reproduction, information on protamine structure is scarce. We, therefore, used molecular dynamics to examine the structures of salmon, bull P1, and human… read more here.
Keywords: structures dynamics; molecular dynamics; dynamics protamine; molecules molecular ... See more keywords
Atomistic structures and dynamics of prenucleation clusters in MOF-2 and MOF-5 syntheses
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11564-4
Abstract: Chemical reactions in solution almost always take place via a series of minute intermediates that are often in rapid equilibrium with each other, and hence hardly characterizable at the level of atomistic molecular structures. We… read more here.
Keywords: prenucleation clusters; atomistic structures; structures dynamics; prenucleation ... See more keywords
Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome
Sign Up to like & getrecommendations! Published in 2018 at "Nature"
DOI: 10.1038/s41586-018-0736-4
Abstract: The proteasome is an ATP-dependent, 2.5-megadalton molecular machine that is responsible for selective protein degradation in eukaryotic cells. Here we present cryo-electron microscopy structures of the substrate-engaged human proteasome in seven conformational states at 2.8–3.6 Å… read more here.
Keywords: engaged human; microscopy; substrate engaged; structures dynamics ... See more keywords
Conserved structures and dynamics in 5′-proximal regions of Betacoronavirus RNA genomes
Sign Up to like & getrecommendations! Published in 2024 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkae144
Abstract: Abstract Betacoronaviruses are a genus within the Coronaviridae family of RNA viruses. They are capable of infecting vertebrates and causing epidemics as well as global pandemics in humans. Mitigating the threat posed by Betacoronaviruses requires… read more here.
Keywords: proximal regions; conserved structures; dynamics proximal; betacoronavirus rna ... See more keywords
Mapping structures and dynamics with frequency-correlated diffusion exchange
Sign Up to like & getrecommendations! Published in 2025 at "Science Advances"
DOI: 10.1126/sciadv.ady8380
Abstract: Understanding molecular motion in diffusion-driven complex environments is critical for designing sustainable materials and improving chemical processes. Here, we introduce a multidimensional nuclear magnetic resonance (NMR) method that captures how molecular populations exchange across different… read more here.
Keywords: dynamics frequency; frequency correlated; mapping structures; structures dynamics ... See more keywords
Insights into Structures and Dynamics of Flavivirus Proteases from NMR Studies
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21072527
Abstract: Nuclear magnetic resonance (NMR) spectroscopy plays important roles in structural biology and drug discovery, as it is a powerful tool to understand protein structures, dynamics, and ligand binding under physiological conditions. The protease of flaviviruses… read more here.
Keywords: nmr studies; dynamics flavivirus; nmr spectroscopy; structures dynamics ... See more keywords