Structures of ferroportin in complex with its specific inhibitor vamifeport
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DOI: 10.1101/2022.08.29.505642
Abstract: A central regulatory mechanism of iron homeostasis in humans involves ferroportin (FPN), the sole cellular iron exporter, and the peptide hormone hepcidin, which inhibits Fe2+ transport and induces internalization and degradation of FPN. Dysregulation of… read more here.
Keywords: structures ferroportin; iron; fpn; inhibitor vamifeport ... See more keywords