Cryo-EM structures of ρ1 GABAA receptors with antagonist and agonist drugs
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-025-61932-6
Abstract: The family of ρ-type GABAA receptors includes potential therapeutic targets in several neurological conditions, and features distinctive pharmacology compared to other subtypes. Here we combine structures, recordings and simulations to characterize the binding and conformational… read more here.
Keywords: agonist drugs; structures gabaa; cryo structures; antagonist agonist ... See more keywords