Determination of tyrosine kinase inhibitor afatinib in rat plasma using LC–MS/MS and its application to in vivo pharmacokinetic studies of afatinib liposomes
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DOI: 10.1016/j.jpba.2018.10.043
Abstract: HighlightsA sensitive and rapid LC–MS/MS method for afatinib, with afatinib dimaleate as a standard.Discussed the stability of afatinib in blood in vitro.Development and pharmacokinetic studies for afatinib liposomes. Abstract A sensitive quantitative liquid chromatography‐tandem mass… read more here.
Keywords: rat plasma; plasma; pharmacokinetic studies; afatinib liposomes ... See more keywords