Docking and QSAR Studies of Aryl-valproic Acid Derivatives to Identify Antiproliferative Agents Targeting the HDAC8.
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DOI: 10.2174/1871520616666161019143219
Abstract: BACKGROUND Histone deacetylase 8 (HDAC8) is a plausible target for the development of novel anticancer drugs using a metal-chelating group and hydrophobic moieties as pharmacophores. It is known that valproic acid (administered as its salt,… read more here.
Keywords: hdac8; valproic acid; studies aryl; docking qsar ... See more keywords