Crystallographic studies of cinnamamide derivatives as a means of searching for anticonvulsant activity.
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DOI: 10.1107/s2053229617013845
Abstract: A cinnamamide (3-phenylprop-2-enamide) core is present in many pharmacologically active compounds. We report three new crystal structures of N-substituted cinnamamide derivatives which were screened for anticonvulsant activity, namely (R,S)-(2E)-N-(2-hydroxypropyl)-3-phenylprop-2-enamide, C12H15NO2, (1), (R,S)-(2E)-N-(1-hydroxybutan-2-yl)-3-phenylprop-2-enamide, C13H17NO2, (2), and… read more here.
Keywords: anticonvulsant activity; cinnamamide derivatives; phenylprop enamide; studies cinnamamide ... See more keywords