Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
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DOI: 10.1016/j.ejmech.2021.113584
Abstract: Replication of SARS-CoV-2, the coronavirus causing COVID-19, requires a main protease (Mpro) to cleave viral proteins. Consequently, Mpro is a target for antiviral agents. We and others previously demonstrated that GC376, a bisulfite prodrug with… read more here.
Keywords: improved sars; mpro inhibitors; cov mpro; solubility ... See more keywords
Case Studies of Improved Relay Auto-tuning of PID Controllers for TITO Systems
Sign Up to like & getrecommendations! Published in 2018 at "Indian Chemical Engineer"
DOI: 10.1080/00194506.2017.1298479
Abstract: Abstract The present work proposes an improved analysis of a simultaneous relay auto-tuning method to calculate the maximum controller gains for two-input two-output (TITO) systems by considering the higher order harmonics. Improved results are obtained… read more here.
Keywords: auto tuning; tito systems; case studies; studies improved ... See more keywords