Bias induced by ignoring double truncation inherent in autopsy-confirmed survival studies of neurodegenerative diseases.
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DOI: 10.1002/sim.8185
Abstract: Neurodegenerative diseases require an autopsy for confirmation of diagnosis. When death is the event of interest, studies based on autopsy-confirmed diagnoses result in right truncated survival times because individuals who live past the end of… read more here.
Keywords: autopsy confirmed; neurodegenerative diseases; double truncation; studies neurodegenerative ... See more keywords
Studies of neurodegenerative diseases using Drosophila and the development of novel approaches for their analysis
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DOI: 10.1080/19336934.2022.2087484
Abstract: ABSTRACT The use of Drosophila in neurodegenerative disease research has contributed to the identification of modifier genes for the pathology. The basis for neurodegenerative disease occurrence in Drosophila is the conservation of genes across species… read more here.
Keywords: studies neurodegenerative; development; drosophila; analysis ... See more keywords