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Published in 2017 at "Crystal Research and Technology"
DOI: 10.1002/crat.201600210
Abstract: Crystals are required to determine three-dimensional structures of proteins and other bio-molecules via X-ray diffraction. This is the prime cause for the keen interest in protein crystallization. Recently published experimental and theoretical studies on protein…
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Keywords:
theoretical studies;
crystallization;
studies protein;
experimental theoretical ... See more keywords
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Published in 2017 at "Chemical reviews"
DOI: 10.1021/acs.chemrev.6b00790
Abstract: X-ray scattering is uniquely suited to the study of disordered systems and thus has the potential to provide insight into dynamic processes where diffraction methods fail. In particular, while X-ray crystallography has been a staple…
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Keywords:
protein structural;
structural dynamics;
studies protein;
ray scattering ... See more keywords
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Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15816
Abstract: Hirudin variants are the most powerful thrombin inhibitors discovered to date, with a lower risk of bleeding than heparin. For anticoagulation, the C‐termini of hirudin variants bind to the exocite I of thrombin. Anticoagulant effects…
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Keywords:
hirudin variants;
studies protein;
molecular dynamic;
pharmacological studies ... See more keywords