Studies towards the synthesis of ertugliflozin from l-Arabinose
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DOI: 10.1016/j.tet.2018.08.005
Abstract: Abstract A new method for the diastereoselective synthesis of enantiomerically pure ertugliflozin was developed. The crucial step involves an aldol condensation between 1-(4-chloro-3-(4-ethoxybenzyl)phenyl)ethanone and (4R,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-2,2-dimethyl-5-((trityloxy)methyl)-1,3-dioxolane-4-carbaldehyde, which was prepared from known 2-C-trityloxymethyl-2,3-O-isopropylidene- l -erythrose (easily accessible… read more here.
Keywords: ertugliflozin arabinose; towards synthesis; studies towards; ertugliflozin ... See more keywords
Towards an Experientialist Understanding of Journalism: Exploring Arts-based Research for Journalism Studies
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DOI: 10.1080/1461670x.2019.1703121
Abstract: ABSTRACT In this paper, we explore the ways in which we can employ arts-based research methods to unpack and represent the diversity and complexity of journalistic experiences and (self) conceptualisations. We address the need to… read more here.
Keywords: journalism; journalism studies; based research; studies towards ... See more keywords
Towards an Articulation of the Material and Visual Turn in Organization Studies
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DOI: 10.1177/0170840618772611
Abstract: Contemporary organizations increasingly rely on images, logos, videos, building materials, graphic and product design, and a range of other material and visual artifacts to compete, communicate, form identity and organize their activities. This Special Issue… read more here.
Keywords: organization studies; material visual; studies towards; visual turn ... See more keywords
Towards a futurist cultural studies
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DOI: 10.1177/1367877920913569
Abstract: Cultural studies is a future-oriented discipline, but it at best maintains tangential connections to futurism, a field of study devoted to the systematic study of the future. Why? This essay endeavors to answer that question.… read more here.
Keywords: studies towards; cultural studies; towards futurist; futurist cultural ... See more keywords
Studies Towards Hypoxia-Activated Prodrugs of PARP Inhibitors
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DOI: 10.3390/molecules24081559
Abstract: Poly(ADP-ribose)polymerase (PARP) inhibitors (PARPi) have recently been approved for the treatment of breast and ovarian tumors with defects in homologous recombination repair (HRR). Although it has been demonstrated that PARPi also sensitize HRR competent tumors… read more here.
Keywords: parp inhibitors; hypoxia activated; activated prodrugs; parpi ... See more keywords