A Spectroscopic Study on the Amyloid‐β Interaction with Clicked Peptide‐Porphyrin Conjugates: a Vision Toward the Detection of Aβ Peptides in Aqueous Solution
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DOI: 10.1002/cbic.202400431
Abstract: Alzheimer's disease (AD) is a multifactorial form of dementia mainly affecting people in the elderly, but no effective cure is available. According to the amyloid hypothesis the aggregation of Amyloid‐β (Aβ) into oligomeric toxic species… read more here.
Keywords: spectroscopic; study amyloid; porphyrin; interaction ... See more keywords
Computational Study of Amyloidβ42 Familial Mutations and Metal Interaction: Impact on Monomers and Aggregates Dynamical Behaviors
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DOI: 10.1021/acs.inorgchem.3c04555
Abstract: One of the main hallmarks of Alzheimer’s Disease is the formation of β-amyloid plaques, whose formation may be enhanced by metal binding or the appearance of familial mutations. In the present study, the simultaneous effect… read more here.
Keywords: computational study; study amyloid; familial mutations; metal binding ... See more keywords