Articles with "study atr" as a keyword



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A first-in-human phase I study of ATR inhibitor M1774 in patients with solid tumors.

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Published in 2021 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2021.39.15_suppl.tps3153

Abstract: TPS3153Background: Ataxia telangiectasia and Rad3-related (ATR) protein kinase plays a critical role in the DNA damage response by sensing and responding to DNA replication stress, and by inducing ... read more here.

Keywords: first human; study atr; atr inhibitor; inhibitor m1774 ... See more keywords