A case–control study to evaluate the impact of the breast screening programme on breast cancer incidence in England
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DOI: 10.1002/cam4.5004
Abstract: There is uncertainty about overdiagnosis in mammography screening. read more here.
Keywords: evaluate impact; control study; study evaluate; breast ... See more keywords
A phase 1 study to evaluate the safety, pharmacology, and feasibility of continuous infusion nelarabine in patients with relapsed and/or refractory lymphoid malignancies
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DOI: 10.1002/cncr.34570
Abstract: Nelarabine is a purine nucleoside analogue prodrug approved for the treatment of relapsed and refractory T‐cell acute lymphoblastic leukemia (R/R T‐ALL) and lymphoblastic lymphoma (T‐LBL). Although effective in R/R T‐ALL, significant neurotoxicity is dose‐limiting and… read more here.
Keywords: pharmacology; study evaluate; relapsed refractory; evaluate safety ... See more keywords
Prospective, multicenter study to evaluate performance and safety of a re‐engineered temporary lead for InterStim™ therapy evaluation
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DOI: 10.1002/nau.24987
Abstract: The basic evaluation or percutaneous nerve evaluation (PNE) is a method to assess pre‐implantation therapeutic response in patients considering sacral neuromodulation for the treatment of refractory overactive bladder. A new PNE lead with a more… read more here.
Keywords: evaluation; study evaluate; performance safety; lead ... See more keywords
A systematic study to evaluate effects of stearic acid on superhydrophobicity and photocatalytic properties of Ag-doped ZnO nanostructures
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DOI: 10.1007/s10854-020-03893-8
Abstract: In the present paper, we employed a co-precipitation method and the modification by stearic acid (SA) to fabrication of silver-(Ag) doped zinc oxide (ZnO) nanostructure surfaces with both superhydrophobicity and photocatalytic properties. The effects of… read more here.
Keywords: study evaluate; superhydrophobicity photocatalytic; stearic acid; photocatalytic properties ... See more keywords
PD37-08 A SINGLE CENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF A NEW ADJUSTABLE ARTIFICIAL URINARY SPHINCTER (VICTO)
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DOI: 10.1097/ju.0000000000000908.08
Abstract: INTRODUCTION AND OBJECTIVE: Aim of the study was to evaluate the efficacy and safety of VICTO system after a follow-up 1yr. METHODS: VICTO is a preconnected adjustable AUS. The pressure in the occluding cuff is… read more here.
Keywords: efficacy safety; study evaluate; evaluate efficacy;
A clinical pilot study to evaluate the efficacy of oral intake of phellinus linteus (sanghuang) extract on knee joint and articular cartilage
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DOI: 10.1097/md.0000000000018912
Abstract: Abstract Background: Knee osteoarthritis (KOA) is the most common form of degenerative arthritis. We used Phellinus linteus (PL), which has been well-known anti-inflammatory function. In this study, we will evaluate if PL extract improves symptoms… read more here.
Keywords: knee; phellinus linteus; study evaluate; study ... See more keywords
Observational study to evaluate discontinuation of monotherapy with cobicistat-boosted darunavir in patients with human immunodeficiency virus
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DOI: 10.1097/md.0000000000032208
Abstract: To evaluate the reasons for changing to monotherapy with protease inhibitors, together with the proportion and reasons for the interruption to treatment, in patients who have been treated at some point with cobicistat-boosted darunavir (DRV/c).… read more here.
Keywords: patients human; study evaluate; human immunodeficiency; monotherapy ... See more keywords
A phase 1 study to evaluate the safety, tolerability and pharmacokinetics of TAK‐041 in healthy participants and patients with stable schizophrenia
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DOI: 10.1111/bcp.15305
Abstract: TAK‐041 (NBI‐1065846), an orally available, investigational, small molecule agonist of GPR139, an orphan G‐protein‐coupled receptor, has shown promise in preclinical studies for the treatment of symptoms associated with schizophrenia. Here, we report the results from… read more here.
Keywords: study evaluate; evaluate safety; phase study; tolerability pharmacokinetics ... See more keywords
A randomized, open‐label, two‐treatment crossover study to evaluate the effect of food on the pharmacokinetics of diazepam nasal spray in healthy adults
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DOI: 10.1111/epi.17459
Abstract: The pharmacokinetics of oral diazepam are affected by food, but food‐effect studies have not been conducted for diazepam nasal spray because it is believed that most absorption occurs via the nasal mucosa. However, gastrointestinal side… read more here.
Keywords: diazepam nasal; food; study evaluate; nasal spray ... See more keywords
Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects
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DOI: 10.1128/aac.02108-21
Abstract: The primary objective of the study was to evaluate the safety and tolerability of single oral doses of sutezolid tablets administered under fasting conditions in healthy adult subjects. The secondary objective was to determine the… read more here.
Keywords: study evaluate; evaluate safety; healthy adult; adult subjects ... See more keywords
Abstract CT192: Phase 1, open-label, single-dose study to evaluate the effect of hepatic impairment on the pharmacokinetics and safety of futibatinib in adult subjects
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DOI: 10.1158/1538-7445.am2023-ct192
Abstract: Background: Futibatinib, an irreversible FGFR1-4 inhibitor, is indicated for the treatment of adult patients with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma harboring FGFR2 gene fusions or other rearrangements. As the primary elimination… read more here.
Keywords: futibatinib; study evaluate; adult subjects; evaluate effect ... See more keywords