Systematic Study of the Glutathione (GSH) Reactivity of N-Phenylacrylamides: 2. Effects of Acrylamide Substitution.
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DOI: 10.1021/acs.jmedchem.0c00749
Abstract: A comprehensive understanding of structure-reactivity relationships is critical to the design and optimization of cysteine-targeted covalent inhibitors. Herein we report glutathione (GSH) reaction rates for N-phenyl acrylamides with varied substitutions at the - and -… read more here.
Keywords: reactivity; gsh reactivity; glutathione gsh; systematic study ... See more keywords