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A Phase 1 Study of KHK4083: A Single‐Blind, Randomized, Placebo‐Controlled Single‐Ascending‐Dose Study in Healthy Adults and an Open‐Label Multiple‐Dose Study in Patients With Ulcerative Colitis

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Published in 2021 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.918

Abstract: OX40 plays an essential role in maintaining late T‐cell proliferation and survival by suppressing apoptosis and by inducing T‐cell memory formation. Here, we report the results of the phase 1 study of KHK4083, a fully… read more here.

Keywords: study khk4083; study; ulcerative colitis; dose ... See more keywords