A focused structure-activity relationship study of psoralen-based immunoproteasome inhibitors.
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DOI: 10.1039/c9md00365g
Abstract: The immunoproteasome is a multicatalytic protease that is predominantly expressed in cells of hematopoietic origin. Its elevated expression has been associated with autoimmune diseases, various types of cancer, and inflammatory diseases. The development of immunoproteasome-selective… read more here.
Keywords: study psoralen; relationship study; focused structure; activity relationship ... See more keywords