Experimental and theoretical study on the regioselective bis- and polyalkylation of 2-mercaptonicotinonitrile and 2-mercaptopyrimidine-5-carbonitrile derivatives
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DOI: 10.1016/j.tet.2017.01.047
Abstract: The synthetic utility of 2-mercaptonicotinonitriles 3 and 4, as well as 2-mercapto-4-oxo-6-phenyl-1,4-dihydropyrimidine-5-carbonitrile 20 as building blocks for novel bis- and poly(pyridines), along with poly(pyrimidines) via alkylation with the corresponding bis- and poy(halo) compounds was investigated.… read more here.
Keywords: theoretical study; regioselective bis; bis polyalkylation; study regioselective ... See more keywords
The Study of Regioselective Acylation of Geniposide by Using Whole-Cell Biocatalysts in Organic Solvents
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DOI: 10.3390/catal15050428
Abstract: Geniposide, the predominant bioactive constituent identified in the traditional Chinese medicine herb Gardenia jasminoides, demonstrates clinically significant pharmacological properties. However, the clinical application of geniposide is significantly limited by its insufficient lipophilicity and consequent compromised… read more here.
Keywords: reaction; study regioselective; whole cell; geniposide ... See more keywords