A phase I study of veliparib (Vel) in combination with oxaliplatin (Ox) and capecitabine (Cap) in advanced solid tumors.
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DOI: 10.1200/jco.2018.36.4_suppl.314
Abstract: 314Background: Poly(ADP-ribose) polymerases (PARP) are activated by DNA strand breaks and important for DNA repair in response to platinum-based chemotherapy. PARP inhibition with Vel might enhance anti-tumor effects of Cap with Ox. This phase I… read more here.
Keywords: combination; vel; study veliparib; phase study ... See more keywords