Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance.
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DOI: 10.1016/j.molmed.2021.04.010
Abstract: Histone eviction and chromatin relaxation are important processes for efficient DNA repair. Poly(ADP) ribose (PAR) polymerase 1 (PARP1) is a key mediator of this process, and disruption of PARP1 activity has a direct impact on… read more here.
Keywords: chromatin remodeling; chromatin; par dependent; studying par ... See more keywords