Abstract 4146303: A Single-Dose of a Novel CasX-Editor Lowers APOC3 Levels In Vivo
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DOI: 10.1161/circ.150.suppl_1.4146303
Abstract: Background: Apolipoprotein C-III (APOC3) is a key regulator of lipid metabolism that inhibits the catabolism and clearance of triglyceride (TG)-rich lipoproteins in the blood. Loss-of-function APOC3 variants are associated with significantly lower TG levels and… read more here.
Keywords: single dose; 1400 lead; stx 1400; lead molecules ... See more keywords