Inhibition of STX17-SNAP29-VAMP8 complex formation by costunolide sensitizes ovarian cancer cells to cisplatin via the AMPK/mTOR signaling pathway.
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DOI: 10.2139/ssrn.4355126
Abstract: Ovarian cancer (OC) is the most common gynecological malignancy. Chemotherapy failure is a major challenge in OC treatment. Targeting autophagy is a promising strategy to enhance the cytotoxicity of chemotherapeutic agents. In this study, we… read more here.
Keywords: stx17 snap29; ovarian cancer; ampk mtor; cells cisplatin ... See more keywords