Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66064-z
Abstract: Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here,… read more here.
Keywords: low frequency; uric acid; serum uric; sua levels ... See more keywords
Serum uric acid levels and the risk of flares among gout patients in a US managed care setting
Sign Up to like & getrecommendations! Published in 2017 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2016.1239193
Abstract: Abstract Objective: Serum uric acid (sUA) levels are causally associated with the risk of gout flares. Our aim was to assess the magnitude of the association and time to first flare among patients in a… read more here.
Keywords: gout flares; sua levels; sua sua; sua ... See more keywords
ATRIAL FIBRILLATION AND ARTERIAL HYPERTENSION. VARIANCE OF SERUM URIC ACID LEVELS IN BOTH DISEASES
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000539127.20937.d0
Abstract: Objective: Atrial fibrillation and arterial hypertension share common risk factors such as obesity, diabetes mellitus, alcohol consumption etc. There is evidence however that the aforementioned risk factors are associated with serum uric acid (SUA) levels.… read more here.
Keywords: atrial fibrillation; fibrillation; arterial hypertension; sua levels ... See more keywords
A study of the relationship between serum uric acid levels and pain in patients with migraine
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000032810
Abstract: Serum uric acid (SUA), the end product of purine metabolism acts as an antioxidant and is related to oxidative stress. It has been reported that SUA may be involved in the pathogenesis of neurodegenerative diseases… read more here.
Keywords: sua levels; headache; patients migraine; study ... See more keywords
Impact of bariatric surgery on serum uric acid levels and the incidence of gout—A meta‐analysis
Sign Up to like & getrecommendations! Published in 2019 at "Obesity Reviews"
DOI: 10.1111/obr.12940
Abstract: Gout is characterized by high serum uric acid (SUA) levels and arthritis. It is associated with obesity and metabolic syndrome. Bariatric surgery has been associated with decreased SUA levels and overall gout incidence. This meta‐analysis… read more here.
Keywords: incidence; bariatric surgery; sua levels; sua ... See more keywords
SAT0421 LONG-TERM URATE-LOWERING THERAPY: IS IT ‘ALL LIFELONG’ NECESSARY?
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.7618
Abstract: Background: It has been published that 13% of gout patients remain in a situation of normouricemia after the suspension of urate-lowering therapy (ULT) and, consequently, would not require lifelong treatment. Prospective and specialized follow-up in… read more here.
Keywords: ult; lowering therapy; sua levels; rheumatology ... See more keywords
POS1130 PHARMACOKINETICS AND SERUM URATE LOWERING EFFECTS OF AR882, A NOVEL, POTENT AND SELECTIVE URICOSURIC AGENT, IN PATIENTS WITH GOUT
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.1284
Abstract: AR882 is a novel, potent and selective uric acid transporter 1 (URAT1) inhibitor in Phase 2 development for the treatment of hyperuricemia and gout. In Phase 1 healthy subject studies, AR882 demonstrated good dose proportionality,… read more here.
Keywords: sua; arthrosi therapeutics; lowering effects; sua levels ... See more keywords
Serum Uric Acid Levels and Nephrosclerosis in a Population-Based Autopsy Study: The Hisayama Study
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Nephrology"
DOI: 10.1159/000521426
Abstract: Introduction: Information regarding the influence of serum uric acid (SUA) levels on pathological changes in the kidney is limited. In this study, we examined the association between SUA levels and pathological findings of nephrosclerosis in… read more here.
Keywords: study; based autopsy; sua levels; glomerular sclerosis ... See more keywords
Association of serum uric acid levels with COVID-19 severity
Sign Up to like & getrecommendations! Published in 2021 at "BMC Endocrine Disorders"
DOI: 10.1186/s12902-021-00745-2
Abstract: Aims Hyperuricemia has attracted increasing attention. However, limited concern has been paid to the potential dangers of lowering serum uric acid (SUA). We observed lower levels of SUA in patients with COVID-19. Therefore, we aim… read more here.
Keywords: uric acid; admission; sua ratio; sua levels ... See more keywords
Washed microbiota transplantation reduces serum uric acid levels in patients with hyperuricaemia
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i11.3401
Abstract: BACKGROUND Previous studies have found that hyperuricaemia (HUA) is closely related to intestinal flora imbalance. AIM The current study investigated the effects and safety of washed microbiota transplantation (WMT) on serum uric acid (SUA) levels… read more here.
Keywords: sua levels; short term; levels patients; sua ... See more keywords
Associations of hyperuricemia and obesity with remission of nonalcoholic fatty liver disease among Chinese men: A retrospective cohort study
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DOI: 10.1371/journal.pone.0192396
Abstract: Nonalcoholic fatty liver disease (NAFLD) is a common chronic disease that is associated with high serum uric acid (SUA) levels, although the effects of high SUA levels on NAFLD remission remain unclear. In addition, it… read more here.
Keywords: remission; sua levels; disease; hyperuricemia obesity ... See more keywords