Re-establishment of efficacy of tofacitinib, an oral JAK inhibitor, after temporary discontinuation in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-04956-1
Abstract: Introduction/objective Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This post-hoc analysis evaluated the effect of temporary discontinuation and reinitiation of tofacitinib on disease control in patients with RA… read more here.
Keywords: treatment; efficacy; efficacy tofacitinib; sub study ... See more keywords
Smoking and overweight associated with masked uncontrolled hypertension: a Hypertension Optimal Treatment (HOT) Sub-Study
Sign Up to like & getrecommendations! Published in 2020 at "Blood Pressure"
DOI: 10.1080/08037051.2020.1787815
Abstract: Abstract Purpose The Hypertension Optimal Treatment (HOT) Study investigated the relationship between target office diastolic blood pressure (BP) ≤80, ≤85 or ≤90 mmHg and cardiovascular morbidity and mortality in 18,790 patients aged 50–80 years. The home BP… read more here.
Keywords: office; home; uncontrolled hypertension; hypertension ... See more keywords
P4772Role of anticoagulation in patients with subclinical AF and its association with cardiovascular events: a SILENT sub study
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz745.1148
Abstract: Atrial fibrillation (AF) is a well-established thromboembolic event risk factor. Episodes of subclinical AF (SCAF) recorded in implantable electronic cardiac devices (IECD) have been related to clinical AF and increased risk of stroke. However, there… read more here.
Keywords: anticoagulation; group; study; rate ... See more keywords
Effect of renal artery revascularization upon cardiac structure and function in atherosclerotic renal artery stenosis: cardiac magnetic resonance sub-study of the ASTRAL trial
Sign Up to like & getrecommendations! Published in 2017 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfw107
Abstract: Background Cardiac abnormalities are frequent in patients with atherosclerotic renovascular disease (ARVD). The Angioplasty and Stenting for Renal Artery Lesions (ASTRAL) trial studied the effect of percutaneous renal revascularization combined with medical therapy compared with… read more here.
Keywords: renal artery; artery; astral trial; versus ... See more keywords
Electrolyte profiles with induced hypothermia: a sub study of a clinical trial evaluating the duration of hypothermia after cardiac arrest.
Sign Up to like & getrecommendations! Published in 2022 at "Acta anaesthesiologica Scandinavica"
DOI: 10.1111/aas.14053
Abstract: BACKGROUND Electrolyte disturbances can result from targeted temperature treatment (TTM) in out-of-hospital cardiac arrest (OHCA) patients. This study explores electrolyte changes in blood and urine in OHCA patients treated with TTM. METHODS This is a… read more here.
Keywords: hypothermia; cardiac arrest; concentration; electrolyte ... See more keywords
Abstract P5-21-23: Evaluation of the drug interaction potential of palbociclib and exemestane – Results from the PEARL pharmacokinetic sub-Study
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs17-p5-21-23
Abstract: Background: Palbociclib (PAL) is an oral cyclin-dependent kinase (CDK) 4/6 inhibitor that is under investigation in multiple oncologic clinical trials and is currently approved for use in combination with aromatase inhibitors (AIs) or fulvestrant (FUL)… read more here.
Keywords: drug; pal exe; study; sub study ... See more keywords
The challenge of planning learning opportunities for clinical medicine: a triangulation study in Iran
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Education"
DOI: 10.1186/s12909-019-1719-3
Abstract: BackgroundAn essential characteristics of clinical education is the need to learn a large number of practical and communication skills along with theoretical knowledge. It is challenging to design learning opportunities (LOs) for clinical setting. We… read more here.
Keywords: medical schools; learning opportunities; medicine; study ... See more keywords
SWOG S1400F (NCT03373760): A phase II study of durvalumab plus tremelimumab for previously treated patients with acquired resistance to PD-1 checkpoint inhibitor therapy and stage IV squamous cell lung cancer (Lung-MAP Sub-study).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.9623
Abstract: 9623Background: The Lung Cancer Master Protocol (Lung-MAP) is designed to evaluate novel targeted therapies in patients with advanced squamous lung carcinoma. In the S1400F sub-study (non-match), w... read more here.
Keywords: lung cancer; study; lung; sub study ... See more keywords
Increased SIRT1 Concentration Following Four Years of Selenium and Q10 Intervention Associated with Reduced Cardiovascular Mortality at 10-Year Follow-Up—Sub-Study of a Previous Prospective Double-Blind Placebo-Controlled Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030759
Abstract: Background: Selenium and coenzyme Q10 (SeQ10) possess antioxidant and anti-inflammatory properties, potentially mediated via Sirtuin1 (SIRT1). We aimed to investigate the influence of a SeQ10 intervention on SIRT1 concentration, with potential interactions with microRNAs. Methods:… read more here.
Keywords: sirt1 concentration; placebo; sub study; prospective double ... See more keywords
Measurement of Barriers, Attitudes, and Expectations for Sitting Less in Pregnancy.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of health behavior"
DOI: 10.5993/ajhb.45.6.1
Abstract: OBJECTIVE Our objective was to develop, validate, and describe findings from an instrument to measure barriers, attitudes, and outcome expectations of sitting less in pregnant women. METHODS This validation (sub-study 1) and descriptive study (sub-study… read more here.
Keywords: sub study; expectations sitting; less pregnancy; sitting less ... See more keywords