Commentary on “High incidence of persistent sub-therapeutic levels of most common AEDs in children with epilepsy receiving polypharmacy”
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsy Research"
DOI: 10.1016/j.eplepsyres.2018.09.010
Abstract: The paper by Czornyj et al. accepts the hypothesis that non-compliance/non-adherence to a therapeutic regimen may well explain the presence of low antiepileptic medication (AEM) blood levels in ambulatory patients but does not accept this… read more here.
Keywords: sub therapeutic; high incidence; commentary high; incidence persistent ... See more keywords
Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study.
Sign Up to like & getrecommendations! Published in 2017 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2017.09.005
Abstract: BACKGROUND Statins and sartans can, in therapeutic doses, induce pleiotropic cardiovascular effects. Similar has recently been shown also for sub-therapeutic doses. We thus explored and compared the cardiovascular pleiotropic efficacy of sub-therapeutic vs. therapeutic doses.… read more here.
Keywords: sub therapeutic; therapeutic doses; doses fluvastatin; fluvastatin valsartan ... See more keywords
Combination of metformin and sub-therapeutic dose of valproic acid prevent valproic acid-induced toxicity in animal model of epilepsy.
Sign Up to like & getrecommendations! Published in 2023 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2023.2168689
Abstract: Valproic acid (VPA) is one of the most prescribed drugs for epilepsy. Extended use of VPA not only induces hepatotoxicity but also impairs the cognitive functions. Metformin has been reported to prevent epileptogenesis and enhance… read more here.
Keywords: combination; therapeutic dose; valproic acid; sub therapeutic ... See more keywords
Evaluating nursery pig responses to in-feed sub-therapeutic antibiotics
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0216070
Abstract: Antibiotics have been used for over 60 years by the swine industry to improve growth performance and feed efficiency. With rising concerns over antimicrobial resistance and government restrictions such as the Veterinary Feed Directive on… read more here.
Keywords: feed; sub therapeutic; action agps; nursery pig ... See more keywords