Association of Onset-to-Treatment Time With Discharge Destination, Mortality, and Complications Among Patients With Aneurysmal Subarachnoid Hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.44039
Abstract: Key Points Question What is the optimal time between symptom onset and treatment after aneurysmal subarachnoid hemorrhage (SAH) to maximize patient outcomes? Findings In this cohort study, more favorable patient outcomes (discharge home and survival… read more here.
Keywords: time; onset treatment; treatment; subarachnoid hemorrhage ... See more keywords
Lactate dehydrogenase predicting mortality in patients with aneurysmal subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51650
Abstract: Lactate dehydrogenase (LDH) has been reported to be associated with outcomes after surgery in patients with aneurysmal subarachnoid hemorrhage (aSAH), but it is unclear if this is independent from other biomarkers and across all aSAH… read more here.
Keywords: aneurysmal subarachnoid; subarachnoid hemorrhage; patients aneurysmal; mortality patients ... See more keywords
A dynamic nomogram for predicting unfavorable prognosis after aneurysmal subarachnoid hemorrhage.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.51789
Abstract: OBJECTIVE The aim of this study was to examine the predictive value of the multiplication of neutrophil and monocyte counts (MNM) in peripheral blood, and develop a new predictive model for the prognosis of patients… read more here.
Keywords: prognosis; aneurysmal subarachnoid; subarachnoid hemorrhage; unfavorable prognosis ... See more keywords
Cilostazol decreases duration of spreading depolarization and spreading ischemia after aneurysmal subarachnoid hemorrhage
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DOI: 10.1002/ana.25361
Abstract: Traditionally, angiographic vasospasm (aVS) has been thought to cause delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). However, successful treatment of aVS alone does not result in improved neurological outcome. Therefore, there may be… read more here.
Keywords: aneurysmal subarachnoid; spreading depolarization; ischemia; subarachnoid hemorrhage ... See more keywords
Soluble ST2 links inflammation to outcome after subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25545
Abstract: To investigate whether soluble growth stimulation expressed gene 2 (sST2), a prognostic marker in cardiovascular and inflammatory disorders, is associated with neurological injury after aneurysmal subarachnoid hemorrhage (SAH). read more here.
Keywords: soluble st2; links inflammation; st2 links; subarachnoid hemorrhage ... See more keywords
Genetically-Determined LDL Cholesterol and Risk of Subarachnoid Hemorrhage.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of neurology"
DOI: 10.1002/ana.26250
Abstract: OBJECTIVE We evaluated whether genetically-elevated Low-Density Lipoprotein Cholesterol (LDL-C) levels are associated with lower risk of intracranial aneurysms and subarachnoid hemorrhage (IA/SAH). METHODS We conducted a two-sample Mendelian Randomization (MR) study. Our primary analysis used… read more here.
Keywords: risk; ldl; cholesterol; subarachnoid hemorrhage ... See more keywords
Proteins of the Lectin Pathway of complement activation at the site of injury in subarachnoid hemorrhage compared with peripheral blood
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1728
Abstract: A subarachnoid hemorrhage (SAH) is a debilitating stroke. Activation of the lectin pathway (LP) of the complement system in SAH patients could worsen the prognosis; however, conflicting results have been reported. This potentially reflects that… read more here.
Keywords: site injury; pathway complement; lectin pathway; subarachnoid hemorrhage ... See more keywords
The protective mechanism of protein kinase R to inhibit neuronal ferroptosis in cerebral injury from subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Brain and Behavior"
DOI: 10.1002/brb3.2722
Abstract: Purpose: To investigate the role and mechanism of protein kinase R (PKR) in subarachnoid hemorrhage (SAH)‐mediated ferroptosis. read more here.
Keywords: mechanism protein; subarachnoid hemorrhage; protein kinase; ferroptosis ... See more keywords
Physical exertion as a risk factor for perimesencephalic nonaneurysmal subarachnoid hemorrhage
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DOI: 10.1002/brb3.2756
Abstract: Perimesencephalic and nonperimesencephalic nonaneurysmal subarachnoid hemorrhage (PM‐naSAH and NPM‐naSAH) have a different bleeding pattern and clinical course. The etiology and risk factors for PM‐naSAH and NPM‐naSAH are unclear. The objective of this study was to… read more here.
Keywords: subarachnoid hemorrhage; nasah npm; risk; nonaneurysmal subarachnoid ... See more keywords
Eupatilin alleviates inflammatory response after subarachnoid hemorrhage by inhibition of TLR4/MyD88/NF‐κB axis
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23317
Abstract: Early brain injury (EBI) is associated with the adverse prognosis of subarachnoid hemorrhage (SAH) patients. The key bioactive component of the Chinese herbal medicine Artemisia asiatica Nakai (Asteraceae) is eupatilin. Recent research reports that eupatilin… read more here.
Keywords: subarachnoid hemorrhage; brain; eupatilin; tlr4 myd88 ... See more keywords
Haplotype analysis of SERPINE1 gene: Risk for aneurysmal subarachnoid hemorrhage and clinical outcomes
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.737
Abstract: Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI‐1 for the regulation of tissue plasminogen activator is… read more here.
Keywords: aneurysmal subarachnoid; haplotype analysis; subarachnoid hemorrhage; serpine1 gene ... See more keywords