Modeling CLN6 with IPSC-derived neural cells
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DOI: 10.1016/j.ymgme.2018.12.299
Abstract: Neuronal ceroid lipofuscionosis type 6 (CLN6) is a neurodegenerative disease associated with dementia, seizures, and retinopathy. The disorder is due to mutations in the CLN6 gene encoding a resident ER transmembrane protein of unknown function. Similar to… read more here.
Keywords: ipsc derived; cln6; neural cells; subc puncta ... See more keywords