miRNALoc: predicting miRNA subcellular localizations based on principal component scores of physico-chemical properties and pseudo compositions of di-nucleotides
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71381-4
Abstract: MicroRNAs (miRNAs) are one kind of non-coding RNA, play vital role in regulating several physiological and developmental processes. Subcellular localization of miRNAs and their abundance in the native cell are central for maintaining physiological homeostasis.… read more here.
Keywords: properties pseudo; component scores; subcellular localizations; principal component ... See more keywords
ncRNALocate-EL: a multi-label ncRNA subcellular locality prediction model based on ensemble learning.
Sign Up to like & getrecommendations! Published in 2023 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elad007
Abstract: Subcellular localizations of ncRNAs are associated with specific functions. Currently, an increasing number of biological researchers are focusing on computational approaches to identify subcellular localizations of ncRNAs. However, the performance of the existing computational methods… read more here.
Keywords: ensemble learning; ncrna subcellular; based ensemble; multi label ... See more keywords
Clarion is a multi-label problem transformation method for identifying mRNA subcellular localizations
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac467
Abstract: Subcellular localization of messenger RNAs (mRNAs) plays a key role in the spatial regulation of gene activity. The functions of mRNAs have been shown to be closely linked with their localizations. As such, understanding of… read more here.
Keywords: mrna subcellular; multi label; clarion; method ... See more keywords
RNAlight: a machine learning model to identify nucleotide features determining RNA subcellular localization
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac509
Abstract: Different RNAs have distinct subcellular localizations. However, nucleotide features that determine these distinct distributions of lncRNAs and mRNAs have yet to be fully addressed. Here, we develop RNAlight, a machine learning model based on LightGBM,… read more here.
Keywords: subcellular localization; localization; nucleotide features; model ... See more keywords
Kinetic principles of ParA2-ATP cycling guide dynamic subcellular localizations in Vibrio cholerae.
Sign Up to like & getrecommendations! Published in 2023 at "Nucleic acids research"
DOI: 10.1093/nar/gkad321
Abstract: Dynamic protein gradients are exploited for the spatial organization and segregation of replicated chromosomes. However, mechanisms of protein gradient formation and how that spatially organizes chromosomes remain poorly understood. Here, we have determined the kinetic… read more here.
Keywords: kinetic principles; para2 atp; vibrio cholerae; principles para2 ... See more keywords