Nanosilicate‐Reinforced Silk Fibroin Hydrogel for Endogenous Regeneration of Both Cartilage and Subchondral Bone
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202200602
Abstract: Osteochondral defects are characterized by injuries to both cartilage and subchondral bone, which is a result of trauma, inflammation, or inappropriate loading. Due to the unique biological properties of subchondral bone and cartilage, developing a… read more here.
Keywords: regeneration; hydrogel; bone; nanocomposite hydrogel ... See more keywords
Transporting Hydrogel via Chinese Acupuncture Needles for Lesion Positioning Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202200079
Abstract: Lesion positioning therapy optimizes medical treatment by directly targeting lesions. However, strong physical barriers greatly hinder its wide use. Here, the Chinese acupuncture needles (CA-needles) with a screw-thread structure at the tip (ST-needle) and the… read more here.
Keywords: therapy; subchondral bone; lesion positioning; acupuncture needles ... See more keywords
Quantifying the Human Subchondral Trabecular Bone Microstructure in Osteoarthritis with Clinical CT
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201692
Abstract: Osteoarthritis (OA) is characterized by critical alterations of the subchondral bone microstructure, besides the well‐known cartilaginous changes. Clinical computed tomography (CT) detection of quantitative 3D microstructural subchondral bone parameters is applied to monitor changes of… read more here.
Keywords: mild moderate; bone; moderate severe; bone microstructure ... See more keywords
Auricular surface morphology and surface area does not influence subchondral bone density distribution in the dysfunctional sacroiliac joint
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Anatomy"
DOI: 10.1002/ca.23980
Abstract: The subchondral lamella of the sacroiliac auricular surface is morphologically inconsistent. Its morpho‐mechanical relationship with dysfunction (SIJD) remains unstudied. Here, the iliac and sacral subchondral bone mineralization is compared between morphological subtypes and in large… read more here.
Keywords: surface area; morphology; surface; auricular surface ... See more keywords
Reduced PDGF‐AA in subchondral bone leads to articular cartilage degeneration after strenuous running
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28427
Abstract: To identify the effects of running on articular cartilage and subchondral bone remodeling, C57BL/6 mice were randomly divided into three groups: control, moderate‐, and strenuous running. Magnetic resonance imaging showed bone marrow lesions in the… read more here.
Keywords: pdgf subchondral; strenuous running; articular cartilage; subchondral bone ... See more keywords
Evaluation of a lanthanide nanoparticle‐based contrast agent for microcomputed tomography of porous channels in subchondral bone
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.25361
Abstract: Osteoarthritis (OA) is a chronic joint disease that causes disability and pain. The osteochondral interface is a gradient tissue region that plays a significant role in maintaining joint health. It has been shown that during… read more here.
Keywords: contrast agent; baybf5 sio2; subchondral bone; porous channels ... See more keywords
The subchondral bone healing after fixation of an osteochondral talar defect is superior in comparison with microfracture
Sign Up to like & getrecommendations! Published in 2017 at "Knee Surgery, Sports Traumatology, Arthroscopy"
DOI: 10.1007/s00167-017-4654-z
Abstract: PurposeArthroscopic bone marrow stimulation (BMS) has been considered the primary surgical treatment for osteochondral defects (OCDs) of the talus. However, fixation has been considered as a good alternative. Recently, a new arthroscopic fixation technique was… read more here.
Keywords: fixation; arthroscopic bms; arthroscopic ldff; subchondral bone ... See more keywords
Co-expression of DKK-1 and Sclerostin in Subchondral Bone of the Proximal Femoral Heads from Osteoarthritic Hips
Sign Up to like & getrecommendations! Published in 2017 at "Calcified Tissue International"
DOI: 10.1007/s00223-017-0246-7
Abstract: BackgroundOsteoarthritis (OA) is a progressively degenerative joint disease influenced by structural and metabolic factors. There is growing evidence that subchondral bone is involved in both symptomatic and structural progression in OA. The Wnt pathway has… read more here.
Keywords: subchondral bone; bone; expression; dkk sclerostin ... See more keywords
Biochemical and Morphological Abnormalities of Subchondral Bone and Their Association with Cartilage Degeneration in Spontaneous Osteoarthritis.
Sign Up to like & getrecommendations! Published in 2021 at "Calcified tissue international"
DOI: 10.1007/s00223-021-00834-3
Abstract: This study aims to investigate how biochemical composition in subchondral bone (SB) relates to the sulfated glycosaminoglycan (sGAG) content of articular cartilage (AC) in the knee joint of guinea pigs from the early to moderate… read more here.
Keywords: osteoarthritis; subchondral bone; guinea pigs; sgag ... See more keywords
The subchondral bone layer and glenoid implant design are relevant for primary stability in glenoid arthroplasty
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-018-2990-1
Abstract: BackgroundClinical studies suggest that reaming of the subchondral bone layer to achieve good implant seating is a risk factor for glenoid loosening. This study aims to evaluate (1) the importance of the subchondral bone layer… read more here.
Keywords: layer; group; subchondral bone; bone layer ... See more keywords
Varying development of femoral and tibial subchondral bone tissue and their interaction with articular cartilage during progressing osteoarthritis
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-020-03480-w
Abstract: Introduction Differences between tibial and femoral joint surfaces and knee compartments concerning coupled bone and cartilage turnover or bone–cartilage cross talk have not been previously examined, although the mechanical and biological interaction of the mineralized… read more here.
Keywords: femoral tibial; articular cartilage; subchondral bone; bone ... See more keywords