Neonatal subchronic toxicity and in vitro genotoxicity studies of the human‐identical milk oligosaccharide 3‐fucosyllactose
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4335
Abstract: Human milk oligosaccharides, such as 3‐fucosyllactose (3‐FL), are bioactive components of breast milk associated with benefits for infant growth and development. Structurally identical compounds (human‐identical milk oligosaccharides—HiMOs) can be produced using microbial fermentation, allowing their… read more here.
Keywords: day; subchronic toxicity; human identical; identical milk ... See more keywords
Subchronic toxicity of low dose propoxur, permethrin, and their combination on the redox status of rat liver.
Sign Up to like & getrecommendations! Published in 2017 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2017.04.023
Abstract: Carbamates and pyrethroids are widely used pesticides. However, their joint toxicity at low doses with long-term exposure remains unknown. Therefore, we investigated the subchronic joint hepatotoxicity of the two representative pesticides within these two classes,… read more here.
Keywords: propoxur permethrin; liver weight; subchronic toxicity; toxicity low ... See more keywords
Subchronic toxicity and concomitant toxicokinetics of long-term oral administration of total alkaloid extracts from seeds of Peganum harmala Linn: A 28-day study in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2019.111866
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE The seeds of Peganum harmala Linn, in which the most abundant active compounds are harmaline and harmine, have been widely used as a traditional medicine in various countries to treat a broad spectrum… read more here.
Keywords: concomitant toxicokinetics; toxicity; subchronic toxicity; day ... See more keywords
Evaluation of 13-week subchronic toxicity of Platycodon grandiflorus (Jacq.) A.DC. root extract in rats.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113621
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Platycodi radix is widely used in traditional herbal medicine for bronchitis, asthma, pulmonary tuberculosis, hypertension, hyperlipidemia, and diabetes. However, data on safety of Platycodi radix are insufficient. AIM OF THE STUDY The present… read more here.
Keywords: water; radix water; subchronic toxicity; platycodi radix ... See more keywords
Acute and subchronic toxicity studies of methanol extract of Polygonum minus leaves in Sprague Dawley rats
Sign Up to like & getrecommendations! Published in 2017 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2017.02.005
Abstract: &NA; Medicinal plant preparations may contain high levels of toxic chemical constituents to potentially cause serious harm to animals and/or humans. Thus, toxicity studies are important to assess the toxic effects of plant derived products.… read more here.
Keywords: methanol extract; toxicity; subchronic toxicity; minus ... See more keywords
Systematic acute and subchronic toxicity evaluation of polysaccharide-protein complex-functionalized selenium nanoparticles with anticancer potency.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm01104h
Abstract: Functionalized selenium nanoparticles (SeNPs) have demonstrated potential for applications in cancer chemotherapy, radio-sensitization, nephroprotection and drug delivery. However, their clinical application requires further systemic safety evaluation. Therefore, in this study, we examine the systematic acute… read more here.
Keywords: acute; functionalized selenium; toxicity; subchronic toxicity ... See more keywords
Acute and subchronic toxicity studies of rhein in immature and d-galactose-induced aged mice and its potential hepatotoxicity mechanisms.
Sign Up to like & getrecommendations! Published in 2020 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2020.1809670
Abstract: Rhein is a key ingredient in many herbal remedies and is widely used. However, herbs containing rhein are frequently associated with poisoning incidents, especially in elderly subjects. Acute and subchronic toxicity of rhein in Kunming… read more here.
Keywords: induced aged; acute subchronic; toxicity; subchronic toxicity ... See more keywords
Subchronic Toxicity Assessment of Phytolacca americana L. (Phytolaccaceae) in F344 Rats
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DOI: 10.1177/1934578x20941656
Abstract: Phytolacca americana L. is traditionally used in Korea, Japan, and China as a diuretic, antibacterial, antiviral, anticancer, and anti-inflammatory agent, and also in the treatment of hepatitis B, psoriasis, edema, and rheumatism. In this study,… read more here.
Keywords: subchronic toxicity; phytolacca americana; f344 rats; body weight ... See more keywords
Mouse Model for Assessing the Subchronic Toxicity of Organophosphate Pesticides
Sign Up to like & getrecommendations! Published in 2018 at "Acta Naturae"
DOI: 10.32607/20758251-2018-10-4-125-128
Abstract: The development of antidotes to organophosphate poisons is an important aspect of modern pharmacology. Recombinant acetylcholinesterase and butyrylcholinesterase are effective DNA-encoded acceptors of organophosphate poisons and, in particular, pesticides. Here, we present the results of… read more here.
Keywords: subchronic toxicity; model; assessing subchronic; model assessing ... See more keywords
Subchronic toxicity of oral deltamethrin in laying chickens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.1079580
Abstract: Pyrethroid pesticides, with low toxicity to birds and mammals and short persistence in the environment, are widely used now. With the development of intensive poultry farming, pesticide application leads to residues in poultry products and… read more here.
Keywords: toxicity oral; subchronic toxicity; laying chickens; toxicity ... See more keywords
Subchronic Toxicity of GmDREB3 Gene Modified Wheat in the Third Generation Wistar Rats
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DOI: 10.3390/plants11141823
Abstract: The aim of the current study was to evaluate the subchronic toxicity of GmDREB3 gene modified wheat in the third generation rats. SPF Wistar rats were fed with transgenic wheat diet (Gm), parental wheat diet… read more here.
Keywords: gmdreb3 gene; subchronic toxicity; third generation; generation ... See more keywords