Comprehensive characterization and simultaneous analysis of overall lipids in reconstructed human epidermis using NPLC/HR-MSn: 1-O-E (EO) Cer, a new ceramide subclass
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-019-02301-3
Abstract: Stratum corneum lipids are responsible for the skin’s barrier function. They are the final product of epidermis lipid biosynthesis. During this process, lipids evolve from simple to complex structures in three main levels respectively (stratum… read more here.
Keywords: nplc msn; human epidermis; comprehensive characterization; epidermis ... See more keywords
Subclass of analytic functions associated with Poisson distribution series
Sign Up to like & getrecommendations! Published in 2020 at "Afrika Matematika"
DOI: 10.1007/s13370-020-00788-z
Abstract: In this paper, we find the necessary and sufficient conditions, inclusion relations for Poisson distribution series $${\mathcal {K}}(m,z)=z+\sum \nolimits _{n=2}^{\infty }\frac{m^{n-1}}{(n-1)!}e^{-m}z^{n}$$ belonging to a subclass $$\mathcal {TS}(\lambda ,\alpha ,\beta )$$ of analytic functions with negative… read more here.
Keywords: distribution series; subclass; poisson distribution; analytic functions ... See more keywords
Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.07.093
Abstract: SUMMARY Lineage analysis of autoreactive B cells can reveal the origins of autoimmunity. In the autoimmune disease pemphigus vulgaris (PV), desmoglein 3 (DSG3) and DSG1 autoantibodies are predominantly of the IgG4 subclass and less frequently… read more here.
Keywords: pemphigus vulgaris; disease pemphigus; iga; autoimmune disease ... See more keywords
Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108754
Abstract: SUMMARY Viral genetic tools that target specific brain cell types could transform basic neuroscience and targeted gene therapy. Here, we use comparative open chromatin analysis to identify thousands of human-neocortical-sub-class-specific putative enhancers from across the… read more here.
Keywords: enhancer; expression; subclass; primate neocortex ... See more keywords
Validation and cross-reactivity pattern assessment of monoclonal antibodies used for the screening of donor-specific IgG antibody subclasses in transplant recipients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2020.112847
Abstract: The screening for IgG subclass donor-specific antibodies (DSAs) in allograft recipients uses IgG1-4 subclass-specific monoclonal antibodies (mAbs) that should be mono-specific. The cross-reactivity discrepancies reported for IgG subclass-specific mAbs warranted a critical cross-reactivity pattern analysis… read more here.
Keywords: subclass specific; igg subclass; subclass; cross reactivity ... See more keywords
Phylogenetic study on three Metacineta species gives a new look at subclass Suctoria systematics
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-94558-1
Abstract: Suctoria is a subclass of ciliates (Phyllopharyngea, Suctoria) distinguished by the presence of a specialized feeding apparatus called tentacles and the absence of ciliature during most of their life cycle. This group of ciliates, particularly… read more here.
Keywords: metacineta; systematics; subclass suctoria; subclass ... See more keywords
Crystal structure and functional analysis of large-terpene synthases belonging to a newly found subclass† †Electronic supplementary information (ESI) available: One PDF document and three movie files. See DOI: 10.1039/c8sc00289d
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c8sc00289d
Abstract: The first crystal structure of a large-terpene synthase elucidated two novel Asp rich motifs and a new subclass of terpene synthases. read more here.
Keywords: large terpene; crystal structure; subclass; terpene synthases ... See more keywords
Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217590120
Abstract: Significance Monoclonal antibodies have been widely used as a therapy for COVID-19. The focus thus far has been on neutralizing antibodies that block viral entry into host cells. However, a typical immune response mostly leads… read more here.
Keywords: spike igg3; switched anti; anti spike; opsonization ... See more keywords
Impact of IgG subclass on molecular properties of monoclonal antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "mAbs"
DOI: 10.1080/19420862.2021.1993768
Abstract: Immunoglobulin G-based monoclonal antibodies (mAbs) have become a dominant class of biotherapeutics in recent decades. Approved antibodies are mainly of the subclasses IgG1, IgG2, and IgG4, as well as their derivatives. Over the decades, the… read more here.
Keywords: igg subclass; impact igg; monoclonal antibodies; molecular properties ... See more keywords
Impact of IgG subclass on monoclonal antibody developability
Sign Up to like & getrecommendations! Published in 2023 at "mAbs"
DOI: 10.1080/19420862.2023.2191302
Abstract: ABSTRACT IgG-based monoclonal antibody therapeutics, which are mainly IgG1, IgG2, and IgG4 subclasses or related variants, have dominated the biotherapeutics field for decades. Multiple laboratories have reported that the IgG subclasses possess different molecular characteristics… read more here.
Keywords: impact igg; igg subclass; monoclonal antibody; subclass ... See more keywords
Immunoglobulin G Subclass Response After Chikungunya Virus Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0055
Abstract: Various vaccines are under development to prevent chikungunya (CHIKV) infection. For the assessment of the CHIKV vaccine-induced antibody response, it is extremely important to understand antibody response after the infection has occurred. Previously, we assessed… read more here.
Keywords: chikungunya; chikv infection; infection; response ... See more keywords