Validation and cross-reactivity pattern assessment of monoclonal antibodies used for the screening of donor-specific IgG antibody subclasses in transplant recipients.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2020.112847
Abstract: The screening for IgG subclass donor-specific antibodies (DSAs) in allograft recipients uses IgG1-4 subclass-specific monoclonal antibodies (mAbs) that should be mono-specific. The cross-reactivity discrepancies reported for IgG subclass-specific mAbs warranted a critical cross-reactivity pattern analysis… read more here.
Keywords: subclass specific; igg subclass; subclass; cross reactivity ... See more keywords
Three Major Gastrointestinal Cancers Could Be Distinguished through Subclass-Specific IgG Glycosylation.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00572
Abstract: Esophageal cancer (EC), gastric cancer (GC), and colorectal cancer (CRC) are three major digestive tract tumors with higher morbidity and mortality due to significant molecular heterogeneity. Altered IgG glycosylation has been observed in inflammatory activities… read more here.
Keywords: igg glycosylation; specific igg; cancer; subclass specific ... See more keywords
Exploring subclass-specific therapeutic agents for hepatocellular carcinoma by informatics-guided drug screen.
Sign Up to like & getrecommendations! Published in 2020 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbaa295
Abstract: Almost all currently approved systemic therapies for hepatocellular carcinoma (HCC) failed to achieve satisfactory therapeutic effect. Exploring tailored treatment strategies for different individuals provides an approach with the potential to maximize clinical benefit. Previously, multiple… read more here.
Keywords: subclass specific; hepatocellular carcinoma; drug; exploring subclass ... See more keywords
Definition of IgG Subclass-Specific Glycopatterns in Idiopathic Membranous Nephropathy: Aberrant IgG Glycoforms in Blood
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094664
Abstract: The podocyte injury, and consequent proteinuria, that characterize the pathology of idiopathic membranous nephropathy (IMN) is mediated by an autoimmune reaction against podocyte antigens. In particular, the activation of pathways leading to abundant renal deposits… read more here.
Keywords: idiopathic membranous; igg subclass; subclass specific; membranous nephropathy ... See more keywords